FlyBase Allele Report: Mdoa\bcd[bcd.1]

General Information

Symbol

Mdoa\bcd^bcd.1

Species

M. domestica

Name

FlyBase ID

FBal0269368

Feature type

allele

Associated gene

Mdoa\bcd

Associated Insertion(s)

Carried in Construct

P{bcd-MDbcd.1}

Transgenic product class

cDNA

(Shaw et al., 2002)

wild_type

(Shaw et al., 2002)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Shaw et al., 2002)

wild_type

(Shaw et al., 2002)

Mutagen

in vitro construct

(Shaw et al., 2002)

Progenitor genotype

Carried in construct

P{bcd-MDbcd.1}

Cytology

Description

bcd regulatory sequences (5' and 3' flanking sequences necessary for maternal expression and anterior localisation) drive expression of a Mdoa\bcd variant 1 cDNA.

(Shaw et al., 2002)

Allele components

Component

Use(s)

Regulatory region(s)

bcd

Encoded product / tool

Mdoa\bcd

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

Mdoa\bcd^bcd.1 is a suppressor | partially of embryonic/larval posterior spiracle | ectopic phenotype of bcd⁶/bcd¹

(Shaw et al., 2002)

Mdoa\bcd^bcd.1 is a suppressor | partially of embryonic thorax phenotype of bcd⁶/bcd¹

(Shaw et al., 2002)

Mdoa\bcd^bcd.1 is a suppressor | partially of embryonic head phenotype of bcd⁶/bcd¹

(Shaw et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Mdoa\bcd^bcd.1 partially rescues the defects seen in embryos derived from bcd⁶/bcd¹ females, with the degree of rescue depending on the Mdoa\bcd^bcd.1 line used. In the strongest rescuing line, complete rescue is seen in a small proportion of embryos, as shown by the presence of all three thoracic segments, a complete head skeleton and other anterior structures such as the mouthhooks and labrum. 7.4% of embryos can develop into fully fertile adults, but most embryos show no rescue.

(Shaw et al., 2002)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Mdoa\bcd^bcd.1

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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