FlyBase Allele Report: Dmel\Ephrin[UAS.cDa]

General Information

Symbol

Dmel\Ephrin^UAS.cDa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Dearborn

FlyBase ID

FBal0269900

Feature type

allele

Associated gene

Dmel\Ephrin

Associated Insertion(s)

Carried in Construct

P{UAS-Ephrin.D}

Key Links

Transgenic product class

wild_type

(Dearborn et al., 2012)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Dearborn et al., 2012)

Mutagen

in vitro construct

(Dearborn et al., 2012)

Progenitor genotype

Carried in construct

P{UAS-Ephrin.D}

Cytology

Description

UASt drives expression of the full-length coding region of Ephrin.

(Dearborn et al., 2012)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Ephrin

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

eye, with Scer\GAL4^hs.2sev

(Dearborn et al., 2012)

Detailed Description

Statement

Reference

Scer\GAL4^hs.2sev-mediated expression of Ephrin^Scer\UAS.cDa results in a moderate rough eye that exhibits very little variation of penetrance.

(Dearborn et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

Ephrin^UAS.cDa, Scer\GAL4^hs.2sev has eye phenotype, enhanceable by Reph^UAS.cDa, Scer\GAL4^hs.2sev

(Dearborn et al., 2012)

Suppressed by

Statement

Reference

Ephrin^UAS.cDa, Scer\GAL4^hs.2sev has eye phenotype, suppressible by Eph^DN.UAS, Scer\GAL4^hs.2sev

(Dearborn et al., 2012)

Ephrin^UAS.cDa, Scer\GAL4^hs.2sev has eye phenotype, suppressible by Eph^KD

(Dearborn et al., 2012)

Ephrin^UAS.cDa, Scer\GAL4^hs.2sev has eye phenotype, suppressible by Reph¹

(Dearborn et al., 2012)

Ephrin^UAS.cDa, Scer\GAL4^hs.2sev has eye phenotype, suppressible by Reph^k08617A

(Dearborn et al., 2012)

Ephrin^UAS.cDa, Scer\GAL4^hs.2sev has eye phenotype, suppressible by Df(2L)sc19-8

(Dearborn et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

The rough eye phenotype of Scer\GAL4^hs.2sev, Ephrin^Scer\UAS.cDa flies is suppressed by co-expression of Eph^DN.Scer\UAS or by Eph^KD.

The rough eye phenotype of Scer\GAL4^hs.2sev, Ephrin^Scer\UAS.cDa flies is strongly suppressed by Reph¹, Reph^k08617A and Df(2L)sc19-8.

The rough eye phenotype of Scer\GAL4^hs.2sev, Ephrin^Scer\UAS.cDa flies is enhanced by co-expression of Reph^Scer\UAS.cDa.

(Dearborn et al., 2012)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Ephrin^Scer\UAS.cDa

Ephrin^UAS.cDa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Dearborn

Secondary FlyBase IDs

References (1)

Report Sections

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