FB2026_02 , released June 18, 2026
Allele: Dmel\RephUAS.cDa
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General Information
Symbol
Dmel\RephUAS.cDa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Dearborn
FlyBase ID
FBal0269898
Feature type
allele
Associated gene
Dmel\Reph
Associated Insertion(s)
Carried in Construct
P{UAS-Reph.D}
Key Links
Transgenic product class
wild_type
(Dearborn et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Dearborn et al., 2012)
Mutagen
in vitro construct
(Dearborn et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-Reph.D}
Cytology
Description

UASt drives expression of a 2kb fragment containing the entire coding region for the 401 amino acid Reph isoform.

(Dearborn et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Reph
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\GAL4elav.PU-mediated expression of RephScer\UAS.cDa results in abnormal medulla architecture, manifest as gaps in the medulla neuropil.

      Somatic cells clones expressing RephScer\UAS.cDa (induced using Scer\GAL4Scer\FRT.Rnor\CD2.αTub84B) are associated with areas of large cortical inclusions and gaps within the medulla neuropil.

      (Dearborn et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      RephUAS.cDa, Scer\GAL4hs.2sev is an enhancer of eye phenotype of EphrinUAS.cDa, Scer\GAL4hs.2sev

      (Dearborn et al., 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The rough eye phenotype of Scer\GAL4hs.2sev, EphrinScer\UAS.cDa flies is enhanced by co-expression of RephScer\UAS.cDa.

      (Dearborn et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4elav.PU/RephUAS.cDa rescues Reph1

      (Dearborn et al., 2012)
      Comments

      Scer\GAL4elav.PU-mediated expression of RephScer\UAS.cDa rescues the homozygous lethality of Reph1.

      (Dearborn et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      RephScer\UAS.cDa
      RephUAS.cDa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Dearborn
      Secondary FlyBase IDs
        References (1)