FlyBase Allele Report: Dmel\Arf1[T31N.UAS]

General Information

Symbol

Dmel\Arf1^T31N.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0270079

Feature type

allele

Associated gene

Dmel\Arf1

Associated Insertion(s)

Carried in Construct

P{UAS-Arf1.T31N}

Key Links

Transgenic product class

dominant_negative_variant

(Dottermusch-Heidel et al., 2012)

missense_variant

(Dottermusch-Heidel et al., 2012)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

dominant_negative_variant

(Dottermusch-Heidel et al., 2012)

missense_variant

(Dottermusch-Heidel et al., 2012)

Mutagen

in vitro construct

(Dottermusch-Heidel et al., 2012)

Progenitor genotype

Carried in construct

P{UAS-Arf1.T31N}

Cytology

Description

UAS regulatory sequences drive expression of a dominant negative form of Arf79F.

(Dottermusch-Heidel et al., 2012)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Arf1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell shape | embryonic stage, with Scer\GAL4^en-e16E

(Greig and Bulgakova, 2020)

lethal - all die before end of larval stage, with Scer\GAL4^en-e16E

(Greig and Bulgakova, 2020)

Phenotype Manifest In

embryonic epidermis, with Scer\GAL4^en-e16E

(Greig and Bulgakova, 2020)

embryonic myoblast, with Scer\GAL4^Mef2.PR

(Dottermusch-Heidel et al., 2012)

Detailed Description

Statement

Reference

Expression of Arf79F^{T31N.Scer\UAS} under the control of Scer\GAL4^Mef2.PR impairs myoblast fusion in some embryos.

(Dottermusch-Heidel et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Arf1^T31N.UAS, Asap^B52/Asap^K23, Scer\GAL4^Toll-6-D42 has lethal - all die before end of second instar larval stage phenotype

(Mallik et al., 2026)

Arf1^T31N.UAS, Asap^B52/Asap^K23, Scer\GAL4^Act5C.PI has lethal - all die before end of second instar larval stage phenotype

(Mallik et al., 2026)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Arf1^DN

(Greig and Bulgakova, 2020)

Arf1^T31N.UAS

Arf79F^{T31N.Scer\UAS}

Arf79F^T31N.UAS

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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