FlyBase Allele Report: Dmel\bsf[NIG.10302R]

General Information

Symbol

Dmel\bsf^NIG.10302R

Species

D. melanogaster

Name

FlyBase ID

FBal0270416

Feature type

allele

Associated gene

Dmel\bsf

Associated Insertion(s)

Carried in Construct

P{NIG.10302R}

Also Known As

UAS-bsfRNAi#1

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Japanese National Institute of Genetics, 2012.5.21)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Japanese National Institute of Genetics, 2012.5.21)

Mutagen

in vitro construct

(Japanese National Institute of Genetics, 2012.5.21)

Progenitor genotype

Carried in construct

P{NIG.10302R}

Cytology

Description

UASt regulatory sequences drive expression of a 500bp inverted repeat.

(Japanese National Institute of Genetics, 2012.5.21)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-10302R

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal developmental rate, with Scer\GAL4^da.PU

(Bratic et al., 2011)

abnormal locomotor behavior, with Scer\GAL4^da.PU

(Bratic et al., 2011)

female semi-sterile, with Scer\GAL4^da.PU

(Bratic et al., 2011)

partially lethal - majority live, with Scer\GAL4^da.PU

(Bratic et al., 2011)

short lived, with Scer\GAL4^da.PU

(Bratic et al., 2011)

Phenotype Manifest In

ovary, with Scer\GAL4^da.PU

(Bratic et al., 2011)

Detailed Description

Statement

Reference

Expression of bsf^NIG.10302R under the control of Scer\GAL4^da.PU and Scer\GAL4^elav.PU does not cause any obvious differences in mitochondrial morphology, compared to controls.

(Pajak et al., 2019)

Scer\GAL4^da.PU bsf^NIG.10302R flies show: a delay in pupal development, with the majority of pupae hatching; a significantly reduced climbing ability; female flies weigh less; continuous crossings result in no offspring; females lay significantly fewer eggs and have ovaries that are significantly reduced in size in comparison with controls; and their life span is drastically reduced compared with controls, with most flies surviving less than 30 days.

(Bratic et al., 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

bsf^NIG.10302R/Scer\GAL4^GMR.PU is an enhancer of eye phenotype of Scer\GAL4^GMR.PU, Zzzz\CTG^i480.UAS.cGa

(Llamusi et al., 2013)