FlyBase Allele Report: Dmel\Ddrgk1[NIG.5862R]

General Information

Symbol

Dmel\Ddrgk1^NIG.5862R

Species

D. melanogaster

Name

FlyBase ID

FBal0274865

Feature type

allele

Associated gene

Dmel\Ddrgk1

Associated Insertion(s)

Carried in Construct

P{NIG.5862R}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Japanese National Institute of Genetics, 2012.5.21)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Japanese National Institute of Genetics, 2012.5.21)

Mutagen

in vitro construct

(Japanese National Institute of Genetics, 2012.5.21)

Progenitor genotype

Carried in construct

P{NIG.5862R}

Cytology

Description

UASt regulatory sequences drive expression of a 500bp inverted repeat.

(Japanese National Institute of Genetics, 2012.5.21)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-5862R

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

adult brain, with Scer\GAL4^elav.PU

(Li et al., 2023)

lysosome | adult stage | increased number, with Scer\GAL4^elav.PU

(Li et al., 2023)

vacuole | adult stage | increased number, with Scer\GAL4^elav.PU

(Li et al., 2023)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has decreased rate of adult locomotory behavior | progressive phenotype, suppressible | partially by Patj^UAS.cBa, Scer\GAL4^elav.PU

(Li et al., 2023)

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has short lived phenotype, suppressible | partially by Patj^UAS.cBa, Scer\GAL4^elav.PU

(Li et al., 2023)

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has increased mortality | adult stage | chemical conditional phenotype, suppressible | partially by Atg9^UAS.GFP, Scer\GAL4^elav.PU

(Li et al., 2023)

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has abnormal oxidative stress response | adult stage phenotype, suppressible | partially by Atg9^UAS.GFP, Scer\GAL4^elav.PU

(Li et al., 2023)

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has increased mortality | adult stage | chemical conditional phenotype, suppressible | partially by puc^HMJ21742, Scer\GAL4^elav.PU

(Li et al., 2023)

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has abnormal oxidative stress response | adult stage phenotype, suppressible | partially by puc^HMJ21742, Scer\GAL4^elav.PU

(Li et al., 2023)

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has decreased rate of adult locomotory behavior | progressive phenotype, suppressible | partially by puc^HMJ21742, Scer\GAL4^elav.PU

(Li et al., 2023)

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has short lived phenotype, suppressible | partially by puc^HMJ21742, Scer\GAL4^elav.PU

(Li et al., 2023)

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has decreased rate of adult locomotory behavior | progressive phenotype, suppressible | partially by puc^E69

(Li et al., 2023)

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has short lived phenotype, suppressible | partially by puc^E69

(Li et al., 2023)

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has decreased rate of adult locomotory behavior | progressive phenotype, suppressible | partially by Atg9^UAS.GFP, Scer\GAL4^elav.PU

(Li et al., 2023)

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has short lived phenotype, suppressible | partially by Atg9^UAS.GFP, Scer\GAL4^elav.PU

(Li et al., 2023)

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has increased cell death | adult stage phenotype, suppressible | partially by Atg9^UAS.GFP, Scer\GAL4^elav.PU

(Li et al., 2023)

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has decreased rate of adult locomotory behavior | progressive phenotype, suppressible | partially by Thor^UAS.cMa, Scer\GAL4^elav.PU

(Li et al., 2023)

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has short lived phenotype, suppressible | partially by Thor^UAS.cMa, Scer\GAL4^elav.PU

(Li et al., 2023)

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has decreased rate of adult locomotory behavior | progressive phenotype, suppressible | partially by S6k^HMJ02231, Scer\GAL4^elav.PU

(Li et al., 2023)

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has short lived phenotype, suppressible by S6k^HMJ02231, Scer\GAL4^elav.PU

(Li et al., 2023)

Phenotype Manifest In

Suppressed by

Statement

Reference

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has adult brain phenotype, suppressible | partially by Atg9^UAS.GFP, Scer\GAL4^elav.PU

(Li et al., 2023)

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has vacuole | increased number | adult stage phenotype, suppressible | partially by Atg9^UAS.GFP, Scer\GAL4^elav.PU

(Li et al., 2023)

Ddrgk1^NIG.5862R, Scer\GAL4^elav.PU has lysosome | increased number | adult stage phenotype, suppressible | partially by Atg9^UAS.GFP, Scer\GAL4^elav.PU

(Li et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

NIG-Fly

5862R-3

P{NIG.5862R}3

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG5862^NIG.5862R

Ddrgk1^NIG.5862R

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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