FlyBase Allele Report: Dmel\wun2[UAS.GFP]

General Information

Symbol

Dmel\wun2^UAS.GFP

Species

D. melanogaster

Name

FlyBase ID

FBal0276701

Feature type

allele

Associated gene

Dmel\wun2

Associated Insertion(s)

Carried in Construct

P{UAS-wun2.GFP}

Key Links

Transgenic product class

wild_type

(Ile et al., 2012)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Ile et al., 2012)

Mutagen

in vitro construct

(Ile et al., 2012)

Progenitor genotype

Carried in construct

P{UAS-wun2.GFP}

Cytology

Description

UASt regulatory sequences drive expression of wun2 which is tagged at the C-terminal end with GFP.

(Ile et al., 2012)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

wun2

Tagged with

GFP

green fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Df(2R)w45-19g, Scer\GAL4^alrm.PD, wun2^EP2650ex34, wun2^UAS.GFP, wun⁴⁹ has abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype, suppressible by Tre1^attP

(Chen et al., 2024)

Df(2R)w45-19g, Scer\GAL4^alrm.PD, wun2^EP2650ex34, wun2^UAS.GFP, wun⁴⁹ has increased cell size | larval stage | somatic clone - tissue specific phenotype, suppressible by Tre1^attP

(Chen et al., 2024)

Suppressor of

Statement

Reference

wun2^UAS.GFP/Scer\GAL4^alrm.PD is a suppressor of abnormal neuroanatomy | larval stage phenotype of Df(2R)w45-19g, wun2^EP2650ex34, wun⁴⁹

(Chen et al., 2024)

wun2^UAS.GFP/Scer\GAL4^alrm.PD is a suppressor of decreased cell size | somatic clone | larval stage phenotype of wun2^EP2650ex34, wun⁴⁹

(Chen et al., 2024)

wun2^UAS.GFP/Scer\GAL4^alrm.PD is a suppressor of abnormal neuroanatomy | somatic clone | larval stage phenotype of wun2^EP2650ex34, wun⁴⁹

(Chen et al., 2024)

Other

Statement

Reference

Df(2R)w45-19g, Scer\GAL4^alrm.PD, wun2^EP2650ex34, wun2^UAS.GFP, wun⁴⁹ has abnormal neuroanatomy | larval stage phenotype

(Chen et al., 2024)

Df(2R)w45-19g, Scer\GAL4^alrm.PD, wun2^EP2650ex34, wun2^UAS.GFP, wun⁴⁹ has increased cell size | larval stage | somatic clone - tissue specific phenotype

(Chen et al., 2024)

Df(2R)w45-19g, Scer\GAL4^Tub.PU, wun2^EP2650ex34, wun2^UAS.GFP, wun⁴⁹ has abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype

(Chen et al., 2024)

Phenotype Manifest In

Suppressed by

Statement

Reference

Df(2R)w45-19g, Scer\GAL4^alrm.PD, wun2^EP2650ex34, wun2^UAS.GFP, wun⁴⁹ has embryonic/larval astrocyte-like glial cell | larval stage | somatic clone - tissue specific phenotype, suppressible by Tre1^attP

(Chen et al., 2024)

Suppressor of

Statement

Reference

wun2^UAS.GFP/Scer\GAL4^alrm.PD is a suppressor of embryonic/larval astrocyte-like glial cell | larval stage phenotype of Df(2R)w45-19g, wun2^EP2650ex34, wun⁴⁹

(Chen et al., 2024)

wun2^UAS.GFP/Scer\GAL4^alrm.PD is a suppressor of embryonic/larval astrocyte-like glial cell | somatic clone | larval stage phenotype of wun2^EP2650ex34, wun⁴⁹

(Chen et al., 2024)

Other

Statement

Reference

Df(2R)w45-19g, Scer\GAL4^alrm.PD, wun2^EP2650ex34, wun2^UAS.GFP, wun⁴⁹ has embryonic/larval astrocyte-like glial cell | larval stage phenotype

(Chen et al., 2024)

Df(2R)w45-19g, Scer\GAL4^Tub.PU, wun2^EP2650ex34, wun2^UAS.GFP, wun⁴⁹ has embryonic/larval astrocyte-like glial cell | larval stage | somatic clone - tissue specific phenotype

(Chen et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of wun2^{Scer\UAS.T:Avic\GFP} under the control of Scer\GAL4^btl.PS completely rescues the tracheal defects that are seen in embryos lacking both maternal and zygotic wun and wun2 function.

(Ile et al., 2012)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

wun2^{Scer\UAS.T:Avic\GFP}

wun2^UAS.GFP

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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