FlyBase Allele Report: Dmel\Tre1[attP]

General Information

Symbol

Dmel\Tre1^attP

Species

D. melanogaster

Name

FlyBase ID

FBal0355453

Feature type

allele

Associated gene

Dmel\Tre1

Associated Insertion(s)

TI{TI}Tre1^attP

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

CRISPR/Cas9

(Rao and Deng, 2019.10.23)

gene targeting by homologous recombination

(Rao and Deng, 2019.10.23)

Progenitor genotype

Associated Insertion(s)

TI{TI}Tre1^attP

Cytology

Description

An attP-Disc\RFP^3xP3.cUa-loxP cassette replaces part of Tre1.

(Rao and Deng, 2019.10.23)

Allele components

Component

Use(s)

Also carries

attP

integrase target site

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

delins

X:5,673,985..5,675,977 [-]

Comment:

A attP-Disc\RFP^3xP3.cUa-loxP cassette replaces the deleted genomic sequence.

Reported_genomic_loc:

X_r6:5673985..5675977

(Rao and Deng, 2019.10.23)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Tre1^attP has abnormal neuroanatomy | adult stage phenotype, enhanceable by Rac1^N17.UAS/Scer\GAL4^alrm.PD

(Chen et al., 2024)

Tre1^attP has decreased size | adult stage | somatic clone phenotype, enhanceable by Rac1^N17.UAS/Scer\GAL4^alrm.PD

(Chen et al., 2024)

Tre1^attP has decreased cell size | adult stage | somatic clone phenotype, enhanceable by Rac1^N17.UAS/Scer\GAL4^alrm.PD

(Chen et al., 2024)

Tre1^attP has abnormal neuroanatomy | adult stage phenotype, enhanceable by Rac1^UAS.cWa/Scer\GAL4^alrm.PD

(Chen et al., 2024)

Tre1^attP has decreased size | adult stage | somatic clone phenotype, enhanceable by Rac1^UAS.cWa/Scer\GAL4^alrm.PD

(Chen et al., 2024)

Tre1^attP has decreased cell size | adult stage | somatic clone phenotype, enhanceable by Rac1^UAS.cWa/Scer\GAL4^alrm.PD

(Chen et al., 2024)

NOT Enhanced by

Statement

Reference

Tre1^attP has abnormal neuroanatomy | larval stage phenotype, non-enhanceable by wun⁴⁹/wun2^EP2650ex34

(Chen et al., 2024)

NOT suppressed by

Statement

Reference

Tre1^attP has abnormal neuroanatomy | larval stage phenotype, non-suppressible by wun⁴⁹/wun2^EP2650ex34

(Chen et al., 2024)

Suppressor of

Statement

Reference

Tre1^attP is a suppressor of abnormal neuroanatomy | larval stage | somatic clone - tissue specific phenotype of Df(2R)w45-19g, Scer\GAL4^alrm.PD, wun2^EP2650ex34, wun2^UAS.GFP, wun⁴⁹

(Chen et al., 2024)

Tre1^attP is a suppressor of increased cell size | larval stage | somatic clone - tissue specific phenotype of Df(2R)w45-19g, Scer\GAL4^alrm.PD, wun2^EP2650ex34, wun2^UAS.GFP, wun⁴⁹

(Chen et al., 2024)

Other

Statement

Reference

Rac1^N17.UAS, Scer\GAL4^alrm.PD, Tre1^attP has decreased rate of adult locomotory behavior phenotype

(Chen et al., 2024)

Phenotype Manifest In

Enhanced by

Statement

Reference

Tre1^attP has adult astrocyte-like glial cell phenotype, enhanceable by Rac1^N17.UAS/Scer\GAL4^alrm.PD

(Chen et al., 2024)

Tre1^attP has actin cytoskeleton | adult stage | somatic clone phenotype, enhanceable by Rac1^N17.UAS/Scer\GAL4^alrm.PD

(Chen et al., 2024)

Tre1^attP has adult astrocyte-like glial cell phenotype, enhanceable by Rac1^UAS.cWa/Scer\GAL4^alrm.PD

(Chen et al., 2024)

Tre1^attP has actin cytoskeleton | adult stage | somatic clone phenotype, enhanceable by Rac1^UAS.cWa/Scer\GAL4^alrm.PD

(Chen et al., 2024)

NOT Enhanced by

Statement

Reference

Tre1^attP has embryonic/larval astrocyte-like glial cell | larval stage phenotype, non-enhanceable by wun⁴⁹/wun2^EP2650ex34

(Chen et al., 2024)

NOT suppressed by

Statement

Reference

Tre1^attP has embryonic/larval astrocyte-like glial cell | larval stage phenotype, non-suppressible by wun⁴⁹/wun2^EP2650ex34

(Chen et al., 2024)

Suppressor of

Statement

Reference

Tre1^attP is a suppressor of embryonic/larval astrocyte-like glial cell | larval stage | somatic clone - tissue specific phenotype of Df(2R)w45-19g, Scer\GAL4^alrm.PD, wun2^EP2650ex34, wun2^UAS.GFP, wun⁴⁹

(Chen et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Tre1^attP is rescued by Tre1^{NAY.UAS.Tag:FLAG}/Scer\GAL4^alrm.PD

(Chen et al., 2024)

Tre1^attP is rescued by Tre1^{UAS.cCa.Tag:FLAG}/Scer\GAL4^alrm.PD

(Chen et al., 2024)

Not rescued by

Tre1^attP is not rescued by Tre1^{AAIIY.UAS.Tag:FLAG}/Scer\GAL4^alrm.PD

(Chen et al., 2024)

Tre1^attP is not rescued by Tre1^{NAY.AAIIY.UAS.Tag:FLAG}/Scer\GAL4^alrm.PD

(Chen et al., 2024)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

84582

w^* TI{TI}Tre1^attP

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

CY05-attp

(Rao and Deng, 2019.10.23)

Tre1-attp

(Rao and Deng, 2019.10.23)

Tre1^attP

(Chen et al., 2024)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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