FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\numbΔAB.UAS.Tag:HA
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General Information
Symbol
Dmel\numbΔAB.UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0276712
Feature type
allele
Associated gene
Dmel\numb
Associated Insertion(s)
Carried in Construct
P{UAS-numb.ΔAB.HA}
Key Links
Transgenic product class
inframe_deletion
(Haenfler et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Haenfler et al., 2012)
Mutagen
in vitro construct
(Haenfler et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-numb.ΔAB.HA}
Cytology
Description

UASt regulatory sequences drive expression of a deleted form of numb, which contains a deletion of the sequence between amino acid residues 42 and 76. The protein is tagged with a Tag:HA epitope.

(Haenfler et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
numb
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of numbΔAB.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4wor.PA has no effect on the maintenance of type II neuroblast identity in larval brains.

      Expression of numbΔAB.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4sca.PU results in a decreased number of scutellar bristles compared to wild type.

      (Haenfler et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The formation of supernumerary type I neuroblasts which is seen in l(2)gl334/l(2)gl3644 larval brains is not suppressed by expression of numbΔAB.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4ase.neuro.

      The formation of supernumerary type I neuroblasts which is seen the brains of larvae expressing aPKCCAAXWT.Scer\UAS under the control of Scer\GAL4wor.PA is not suppressed by co-expression of numbΔAB.Scer\UAS.T:Ivir\HA1.

      (Haenfler et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      numbΔAB.Scer\UAS.T:Ivir\HA1
      numbΔAB.UAS.Tag:HA
      numbΔAB
      (Haenfler et al., 2012)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)