FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\nanosALL.Tag:MYC
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General Information
Symbol
Dmel\nanosALL.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0276737
Feature type
allele
Associated gene
Dmel\nanos
Associated Insertion(s)
Carried in Construct
P{nanos-myc.ALL}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Chau et al., 2012)
Progenitor genotype
nanosWT.Tag:MYC
(Chau et al., 2012)
Carried in construct
P{nanos-myc.ALL}
Cytology
Description

Mutation of all three Sxl binding sites in the nos sequence.

(Chau et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
nanos
Encoded product / tool
nanos
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of nosALL.T:Hsap\MYC in a wild-type background has no apparent impact on germ cell differentiation.

      (Chau et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Statement
      Reference

      bam[+]/bamΔ86, nanosALL.Tag:MYC has germarium phenotype

      (Chau et al., 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      3 day old females expressing nosALL.T:Hsap\MYC in a bamΔ86/+ background show a modest but consistent increase in the average number of spectrosome-containing cells per germarium which is accompanied by a statistically significant loss of differentiated cysts. This effect is more pronounced in 20 day old females.

      (Chau et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      nanosALL.Tag:MYC
      nosALL.T:Hsap\MYC
      nosALL.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (2)