FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\msl-3ΔCD.Tag:TAP
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General Information
Symbol
Dmel\msl-3ΔCD.Tag:TAP
Species
D. melanogaster
Name
FlyBase ID
FBal0277753
Feature type
allele
Associated gene
Dmel\msl-3
Associated Insertion(s)
Carried in Construct
M{msl-3-TAP.ΔCD}
Key Links
Transgenic product class
start_lost
(Sural et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
start_lost
(Sural et al., 2008)
Mutagen
in vitro construct
(Sural et al., 2008)
Progenitor genotype
Carried in construct
M{msl-3-TAP.ΔCD}
Cytology
Description

A mutated msl-3 coding sequence is fused to Tag:TAP and driven by an endogenous msl-3 promoter. The msl-3 sequence contains a mutated methionine start codon that leads to the overproduction of a naturally occurring short form that initiates at Met127, downstream of the chromodomain.

(Sural et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
msl-3
Encoded product / tool
msl-3
Tagged with
Tag:TAP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous mutant msl-31 flies carrying msl-3ΔCD.T:Zzzz\TAP display a 2-day developmental delay with respect to wild-type controls and exhibit held-out wings. Adult males are unhealthy and infertile.

      (Sural et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      msl-3ΔCD.Tag:TAP partially rescues msl-31

      (Sural et al., 2008)
      Comments

      Homozygous mutant msl-31 flies carrying msl-3ΔCD.T:Zzzz\TAP display a 2-day developmental delay with respect to wild-type controls and exhibit held-out wings. Adult males are unhealthy and infertile.

      (Sural et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      msl-3ΔCD.T:Zzzz\TAP
      msl-3ΔCD.Tag:TAP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)