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General Information
Symbol
BacA\p35UASp.cBa
Species
N. Autographa californica nucleopolyhedrovirus
Name
FlyBase ID
FBal0278239
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASp regulatory sequences drive expression of BacA\p35.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The eyes of female flies expressing BacA\p35Scer\UAS.P\T.cBa under the control of Scer\GAL4GMR.PF are 20% larger than wild type. No increase is seen in male flies.

Expression of BacA\p35Scer\UAS.P\T.cBa under the control of both Scer\GAL4nos.PG and Scer\GAL4nos.UTR.T:Hsim\VP16 results in defective egg chambers during mid-oogenesis (stages 7-9), characterised by a lack of follicle cells and the presence of large, uncondensed nurse cell nuclei. Approximately 20% of stage 14 egg chambers show uncondensed, persisting nurse cell nuclei.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

Expression of BacA\p35Scer\UAS.P\T.cBa partially rescues the eye phenotypes seen when Zzzz\E4orf4Scer\UAS.cPa is expressed under the control of Scer\GAL4GMR.PF at 24[o]C. In females the resulting eye size is comparable to wild type, whereas males eyes are ~85% the size of those in wild type flies. Eyes still appear rough and shape remains disrupted.

Expression of BacA\p35Scer\UAS.P\T.cBa rescues the eye phenotypes seen when rprScer\UAS.cZa is expressed under the control of Scer\GAL4GMR.PF at 24[o]C. In females, eye size is increased compared to wild type (but is still small compared to the expression of BacA\p35Scer\UAS.P\T.cBa alone), whereas in males the eye size seen is comparable to that seen in wild type. Expression of BacA\p35Scer\UAS.P\T.cBa eliminates eye roughness in both males and females.

Expression of BacA\p35Scer\UAS.P\T.cBa completely suppresses the lethality seen when rprScer\UAS.C is expressed under the control of Scer\GAL4GMR.PF at 24[o]C.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
BacA\p35Scer\UAS.P\T.cBa
BacA\p35UASp.cBa
Name Synonyms
Secondary FlyBase IDs
    References (2)