FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Fer2LCHUAS.cLa
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General Information
Symbol
Dmel\Fer2LCHUAS.cLa
Species
D. melanogaster
Name
FlyBase ID
FBal0278312
Feature type
allele
Associated gene
Dmel\Fer2LCH
Associated Insertion(s)
Carried in Construct
P{UAS-Fer2LCH.L}
Key Links
Transgenic product class
wild_type
(Li, 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Li, 2010)
Mutagen
in vitro construct
(Li, 2010)
Progenitor genotype
Carried in construct
P{UAS-Fer2LCH.L}
Cytology
Description

UAS regulatory sequences drive expression of Fer2LCH coding sequences.

(Li, 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Fer2LCH
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Ubiquitous co-expresson of Fer1HCHScer\UAS.cLa and Fer2LCHScer\UAS.cLa, under the control of Scer\GAL4Act5C.PI does not generate a significant difference in viability or body weight. When these flies are grown in a nutrient-poor diet containing only 33% of the yeast present in a normal diet, these flies show improved viability (by ~20%), increased body weight (by ~10% for males and ~15% for females), and a shortened period for adult emergence (by ~4.5 days, or 18%).

      (Li, 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4Act5C.PI/Fer2LCHUAS.cLa rescues Fer2LCHneo60

      (Li, 2010)
      Comments

      Ubiquitous expression of Fer2LCHScer\UAS.cLa under the control of Scer\GAL4Act5C.PI rescues the first instar larval stage lethality seen in Fer2LCHneo60 and Fer2LCH00035 mutants.

      (Li, 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Fer2LCHScer\UAS.cLa
      Fer2LCHUAS.cLa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)