FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Fer2LCHneo60
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General Information
Symbol
Dmel\Fer2LCHneo60
Species
D. melanogaster
Name
FlyBase ID
FBal0011070
Feature type
allele
Associated gene
Dmel\Fer2LCH
Associated Insertion(s)
P{hsneo}Fer2LCHneo60
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Cooley et al., 1988)
Progenitor genotype
Associated Insertion(s)
P{hsneo}Fer2LCHneo60
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The lethality seen in homozygous or hemizygous Fer2LCHneo60 mutants cannot be rescued by the addition of iron.

      Fer2LCHneo60 mutants grow to mid-first instar after hatching and then stop growing. They are arrested at this stage but survive for approximately 7 days before dying.

      Fer2LCHneo60 mutant larvae show diminished BrdU incorporation and triacylglycerol levels 18hrs after hatching, as found in starved wild-type flies.

      (Li, 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Fer2LCH[+]/Fer2LCHneo60 is an enhancer of scutellar bristle | increased number phenotype of SsdpL7

      (Bronstein et al., 2010)
      NOT Enhancer of
      Statement
      Reference

      Fer2LCH[+]/Fer2LCHneo60 is a non-enhancer of wing margin phenotype of Bx2

      (Bronstein et al., 2010)
      Suppressor of
      Statement
      Reference

      Fer2LCH[+]/Fer2LCHneo60 is a suppressor of scutellar bristle | increased number phenotype of Chie5.5

      (Bronstein et al., 2010)
      NOT Suppressor of
      Statement
      Reference

      Fer2LCH[+]/Fer2LCHneo60 is a non-suppressor of wing margin phenotype of Bx2

      (Bronstein et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Fer2LCHneo60 is rescued by Scer\GAL4Act5C.PI/Fer2LCHUAS.cLa

      (Li, 2010)
      Comments

      Ubiquitous expression of Fer2LCHScer\UAS.cLa under the control of Scer\GAL4Act5C.PI rescues the first instar larval stage lethality seen in Fer2LCHneo60 mutants.

      (Li, 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      A. Spradling.

      Cooley et al.

      (Cooley et al., 1988)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Fer2LCHneo60
      (Bronstein et al., 2010, Li, 2010)
      l(3)neo60
      (Beaton, 1999.12.12)
      l(3)neo601
      (Cooley et al., 1988)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)