FlyBase Allele Report: Dmel\wdb[HMS01864]

General Information

Symbol

Dmel\wdb^HMS01864

Species

D. melanogaster

Name

FlyBase ID

FBal0278981

Feature type

allele

Associated gene

Dmel\wdb

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS01864}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS01864}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS01864

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Females heterozygous for wdb^HMS01864 and Scer\GAL4^{mat.αTub67C.T:Hsim\VP16} crossed to wdb^HMS01864 males results in: 15% hatching; egg/embryonic phenotype: "terminal defects, blobbed and empty"; maternal effect.

(Sopko et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

wrd^Δ/Df(3R)189, Scer\GAL4^{VP16.mat.αTub67C}, wdb^HMS01864 has female semi-sterile phenotype

(Jang et al., 2021)

wrd^Δ/Df(3R)189, Scer\GAL4^{VP16.mat.αTub67C}, wdb^HMS01864 has abnormal meiotic cell cycle | oogenesis phenotype

(Jang et al., 2021)

Scer\GAL4^{VP16.mat.αTub67C}, wdb^HMS01864, wrd^GL00671 has female sterile phenotype

(Jang et al., 2021)

Scer\GAL4^{VP16.mat.αTub67C}, wdb^HMS01864, wrd^GL00671 has abnormal meiotic cell cycle | oogenesis phenotype

(Jang et al., 2021)

Scer\GAL4^{VP16.nanos.UTR}, wdb^HMS01864, wrd^GL00671 has female sterile phenotype

(Jang et al., 2021)

Ndc80^GL00625, Scer\GAL4^{VP16.mat.αTub67C}, wdb^HMS01864, wrd^Δ has abnormal meiotic cell cycle | oogenesis phenotype

(Jang et al., 2021)

Phenotype Manifest In

Other

Statement

Reference

wrd^Δ/Df(3R)189, Scer\GAL4^{VP16.mat.αTub67C}, wdb^HMS01864 has oocyte phenotype

(Jang et al., 2021)

Scer\GAL4^{VP16.mat.αTub67C}, wdb^HMS01864, wrd^GL00671 has oocyte phenotype

(Jang et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

38950

y¹ sc^* v¹ sev²¹; P{TRiP.HMS01864}attP2/TM3, Sb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

wdb^HMS01864

(Shapiro et al., 2025, Jang et al., 2021)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

Open Close