FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mir-277UAS.cTa
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General Information
Symbol
Dmel\mir-277UAS.cTa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Tan
FlyBase ID
FBal0280060
Feature type
allele
Associated gene
Dmel\mir-277
Associated Insertion(s)
Carried in Construct
P{UAS-mir-277.T}
Key Links
Transgenic product class
wild_type
(Tan et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Tan et al., 2012)
Mutagen
in vitro construct
(Tan et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-mir-277.T}
Cytology
Description

UAS regulatory sequences drive expression of mir-277.

(Tan et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
mir-277
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  neurodegenerative disease
      modeled by Zzzz\CGG90.UAS.EGFP
      (Tan et al., 2012)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      7 day old flies expressing mir-277Scer\UAS.cTa under the control of Scer\GAL4GMR.PF exhibit a mild rough eye phenotype.

      (Tan et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of mir-277Scer\UAS.cTa enhances the eye phenotype seen when Avic\GFPFmr1.CGG90.E.Scer\UAS is expressed under the control of Scer\GAL4GMR.PF. Enhanced disorganised, fused ommatidia are seen compared with expression of Avic\GFPFmr1.CGG90.E.Scer\UAS alone.

      (Tan et al., 2012)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      mir-277Scer\UAS.cTa
      mir-277UAS.cTa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Tan
      Secondary FlyBase IDs
        References (1)