FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\polopA2.GFP
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General Information
Symbol
Dmel\polopA2.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0280094
Feature type
allele
Associated gene
Dmel\polo
Associated Insertion(s)
Carried in Construct
P{GFP-polo.pA2}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Pinto et al., 2011)
Progenitor genotype
poloGFP
(Pinto et al., 2011)
Carried in construct
P{GFP-polo.pA2}
Cytology
Description

The pA2 signal and the entire downstream region are deleted from the polo 3'UTR. This leads to this transgene only expressing the shorter polo transcript. Tagged at the N-terminus with GFP.

(Pinto et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
polo
Encoded product / tool
polo
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      polopA2.GFP fails to rescue poloS025604

      (Pinto et al., 2011)
      Comments

      Nearly all polopA2.T:Avic\GFP;poloS025604 flies die during pupariation.

      (Pinto et al., 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      The longer polo transcript derived from the pA2 signal is essential for the proliferation of abdominal histoblasts at the onset of pupal metamorphosis.

      (Pinto et al., 2011)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      polopA2.GFP
      polopA2.T:Avic\GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)