FlyBase Allele Report: Dmel\Jabba[zl01]

General Information

Symbol

Dmel\Jabba^zl01

Species

D. melanogaster

Name

FlyBase ID

FBal0280318

Feature type

allele

Associated gene

Dmel\Jabba

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Li et al., 2012)

Progenitor genotype

P{XP}d03001

(Li et al., 2012)

Cytology

Description

Imprecise excision of the progenitor insertion, resulting in a 660bp deletion of genomic sequences.

(Li et al., 2012)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

fertile

(Li et al., 2012)

viable

(Li et al., 2012)

Phenotype Manifest In

lipid droplet

(Li et al., 2012)

lipid droplet | embryonic stage

(Kilwein et al., 2023)

Detailed Description

Statement

Reference

Mutant embryos have normal overall triglyceride content and have abundant lipid droplets. However, the droplets are less evenly distributed than in wild type and are often clustered.

Embryos derived from mutant females hatch at wild-type rates and give rise to fertile adults.

(Li et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Df(3R)3450/+, Jabba^zl01 has lethal phenotype

(Li et al., 2012)

Jabba^zl01, Slbp[+]/Slbp¹⁰ has lethal phenotype

(Li et al., 2012)

His2Av[+]/His2Av⁸¹⁰, Jabba^zl01 has partially lethal - majority die phenotype

(Li et al., 2012)

Df(3R)3450/+, Jabba^zl01 has lethal | maternal effect phenotype

(Li et al., 2012)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Embryos derived from Jabba^zl01/Jabba^zl01 ; Df(3R)3450/+ females typically reach the syncytial stages, but then become morphologically abnormal. Cellularisation, if initiated at all, frequently proceeds abnormally and most of the embryos fail to hatch. The nuclei in the blastoderm embryos are often different sizes and are misshapen and unevenly spaced. Trailing chromosomes are seen during anaphase and telophase. Nuclei are seen between the cortex and central yolk and abundant free centrosomes are seen at the cortex, indicating nuclear fallout.

(Li et al., 2012)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Jabba^z101

(Thomalla et al., 2025)

Jabba^zl01

(Thomalla et al., 2025, Kilwein et al., 2023, Stephenson et al., 2021, Johnson et al., 2018, Li et al., 2012, Li et al., 2012)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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