FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Prx2RNAi.UAS
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General Information
Symbol
Dmel\Prx2RNAi.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0280346
Feature type
allele
Associated gene
Dmel\Prx2
Associated Insertion(s)
Carried in Construct
P{UAS-Prx2.RNAi}
Key Links
Transgenic product class
RNAi_reagent
(Nam et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Nam et al., 2012)
Mutagen
in vitro construct
(Nam et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-Prx2.RNAi}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat that targets Jafrac1.

(Nam et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Prx2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Prx2RNAi.UAS/Scer\GAL4da.G32 is a suppressor | partially of short lived | conditional phenotype of Hayan1

      (Nam et al., 2012)

      Prx2RNAi.UAS/Scer\GAL4ChAT.7.4 is a suppressor | partially of short lived | conditional phenotype of Hayan1

      (Nam et al., 2012)

      Prx2RNAi.UAS/Scer\GAL4da.G32 is a suppressor of short lived | conditional phenotype of PPO1Bc

      (Nam et al., 2012)
      NOT Suppressor of
      Statement
      Reference

      Prx2RNAi.UAS/Scer\GAL4He.PZ is a non-suppressor of short lived | conditional phenotype of Hayan1

      (Nam et al., 2012)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Jafrac1dsRNA.Scer\UAS under the control of Scer\GAL4da.G32 rescues the reduced survival rate seen in Bc1 mutant flies subjected to severe wounding.

      Expression of Jafrac1dsRNA.Scer\UAS under the control of Scer\GAL4da.G32 partially suppresses the wound-induced mortality seen in Hayan1 mutants. The mortality is also rescued when Jafrac1dsRNA.Scer\UAS is expressed in neurons under the control of Scer\GAL4Cha.7.4, but not when it is expressed in hemocytes under the control of Scer\GAL4He.PZ.

      (Nam et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Jafrac1dsRNA.Scer\UAS
      Jafrac1dsRNA.UAS
      Prx2RNAi.UAS
      Prx2dsRNA.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)