FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Prx2UAS.cDa
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General Information
Symbol
Dmel\Prx2UAS.cDa
Species
D. melanogaster
Name
FlyBase ID
FBal0280980
Feature type
allele
Associated gene
Dmel\Prx2
Associated Insertion(s)
Carried in Construct
P{UAS-Prx2.D}
Key Links
Transgenic product class
wild_type
(Degennaro et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Degennaro et al., 2011)
Mutagen
in vitro construct
(Degennaro et al., 2011)
Progenitor genotype
Carried in construct
P{UAS-Prx2.D}
Cytology
Description

UAS regulatory sequences drive expression of a full-length Jafrac1 open reading frame.

(Degennaro et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Prx2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      Prx2UAS.cDa, Scer\GAL4ppk.PU is a non-suppressor of abnormal neuroanatomy | P-stage phenotype of Scer\GAL4ppk.PU, cncGD4437

      (Chew et al., 2021)
      Phenotype Manifest In
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4nanos.PG/Prx2UAS.cDa rescues Prx2KG05372

      (Degennaro et al., 2011)
      Fails to rescue

      Scer\GAL4nullo.PG/Prx2UAS.cDa fails to rescue Prx2KG05372

      (Degennaro et al., 2011)
      Comments

      Expression of Jafrac1Scer\UAS.cDa in Jafrac1KG05372 mutants under the control of Scer\GAL4nos.PG reduces the penetrance of the primordial germline cell adhesion defect phenotype in Jafrac1KG05372 mutants from 73% of embryos to 8% of embryos, and a reduction in the average number of primordial germline cells left outside the midgut from 6 to 0.4.

      Somatic expression of Jafrac1Scer\UAS.cDa under the control of Scer\GAL4nullo.PG does not significantly alter the Jafrac1KG05372 mutant phenotype, with an average of 7.2 PGCs left out of the midgut.

      (Degennaro et al., 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Jafrac1Scer\UAS.cDa
      Jafrac1UAS.cDa
      Prx2UAS.cDa
      Name Synonyms
      Secondary FlyBase IDs
        References (2)