FlyBase Allele Report: Dmel\syd[GLC01419]

General Information

Symbol

Dmel\syd^GLC01419

Species

D. melanogaster

Name

FlyBase ID

FBal0281279

Feature type

allele

Associated gene

Dmel\syd

Associated Insertion(s)

Carried in Construct

P{TRiP.GLC01419}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.GLC01419}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-GLC01419

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates Alzheimer's disease 1

modeled by Hsap\APP^{695-Swedish.UAS.Tag:MYC}

(Du et al., 2021)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased size | adult stage, with Scer\GAL4^en.PU

(Ahmad et al., 2021)

decreased size | adult stage, with Scer\GAL4^nub.PU

(Ahmad et al., 2021)

decreased size | adult stage, with Scer\GAL4^ptc.PU

(Ahmad et al., 2021)

increased cell death | larval stage, with Scer\GAL4^en.PU

(Ahmad et al., 2021)

visible | adult stage, with Scer\GAL4^nub.PU

(Ahmad et al., 2021)

visible | adult stage, with Scer\GAL4^ptc.PU

(Ahmad et al., 2021)

Phenotype Manifest In

wing, with Scer\GAL4^en.PU

(Ahmad et al., 2021)

wing, with Scer\GAL4^nub.PU

(Ahmad et al., 2021)

wing, with Scer\GAL4^ptc.PU

(Ahmad et al., 2021)

wing disc posterior compartment, with Scer\GAL4^en.PU

(Ahmad et al., 2021)

Detailed Description

Statement

Reference

The expression of syd^GLC01419 under the control of Scer\GAL4^nub.PU, Scer\GAL4^en.PU or Scer\GAL4^ptc.PU induces a small wing; Scer\GAL4^en.PU-driven expression leads to apoptosis in the posterior compartment of the wing disc.

(Ahmad et al., 2021)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Scer\GAL4^ptc.PU, syd^GLC01419 has visible | adult stage phenotype, non-enhanceable by bsk^DN.UAS.cUa/Scer\GAL4^ptc.PU

(Ahmad et al., 2021)

Scer\GAL4^ptc.PU, syd^GLC01419 has decreased size | adult stage phenotype, non-enhanceable by bsk^DN.UAS.cUa/Scer\GAL4^ptc.PU

(Ahmad et al., 2021)

Suppressed by

Statement

Reference

Scer\GAL4^nub.PU, syd^GLC01419 has decreased size | adult stage phenotype, suppressible by Scer\GAL4^nub.PU/hpo^HMS00006

(Ahmad et al., 2021)

Scer\GAL4^nub.PU, syd^GLC01419 has visible | adult stage phenotype, suppressible by Scer\GAL4^nub.PU/hpo^HMS00006

(Ahmad et al., 2021)

Scer\GAL4^nub.PU, syd^GLC01419 has decreased size | adult stage phenotype, suppressible | partially by Diap1^33-1s/Diap1[+]

(Ahmad et al., 2021)

Scer\GAL4^nub.PU, syd^GLC01419 has decreased size | adult stage phenotype, suppressible | partially by Dronc⁵¹/Dronc[+]

(Ahmad et al., 2021)

Scer\GAL4^nub.PU, syd^GLC01419 has visible | adult stage phenotype, suppressible | partially by Diap1^33-1s/Diap1[+]

(Ahmad et al., 2021)

Scer\GAL4^nub.PU, syd^GLC01419 has visible | adult stage phenotype, suppressible | partially by Dronc⁵¹/Dronc[+]

(Ahmad et al., 2021)

NOT Enhancer of

Statement

Reference

syd^GLC01419/Scer\GAL4^ptc.PU is a non-enhancer of visible | adult stage phenotype of Scer\GAL4^ptc.PU, bsk^DN.UAS.cUa

(Ahmad et al., 2021)

syd^GLC01419/Scer\GAL4^ptc.PU is a non-enhancer of decreased size | adult stage phenotype of Scer\GAL4^ptc.PU, bsk^DN.UAS.cUa

(Ahmad et al., 2021)

Suppressor of

Statement

Reference

syd^GLC01419/Scer\GAL4^ptc.PU is a suppressor | partially of increased size | larval stage phenotype of Scer\GAL4^ptc.PU, yki^UAS.cHa

(Ahmad et al., 2021)

Scer\GAL4^hh.PU/syd^GLC01419 is a suppressor | partially of increased size | larval stage phenotype of Scer\GAL4^hh.PU, yki^UAS.cHa

(Ahmad et al., 2021)

Scer\GAL4^nub.PU/syd^GLC01419 is a suppressor | partially of increased size | larval stage phenotype of Scer\GAL4^nub.PU, yki^UAS.cHa

(Ahmad et al., 2021)

Scer\GAL4^nub.PU/syd^GLC01419 is a suppressor of increased size | adult stage phenotype of Scer\GAL4^nub.PU, hpo^HMS00006

(Ahmad et al., 2021)

Scer\GAL4^nub.PU/syd^GLC01419 is a suppressor of visible | adult stage phenotype of Scer\GAL4^nub.PU, hpo^HMS00006

(Ahmad et al., 2021)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Scer\GAL4^ptc.PU, syd^GLC01419 has wing phenotype, non-enhanceable by bsk^DN.UAS.cUa/Scer\GAL4^ptc.PU

(Ahmad et al., 2021)

Suppressed by

Statement

Reference

Scer\GAL4^nub.PU, syd^GLC01419 has wing phenotype, suppressible | partially by Scer\GAL4^nub.PU/hpo^HMS00006

(Ahmad et al., 2021)

NOT Enhancer of

Statement

Reference

syd^GLC01419/Scer\GAL4^ptc.PU is a non-enhancer of wing phenotype of Scer\GAL4^ptc.PU, bsk^DN.UAS.cUa

(Ahmad et al., 2021)

Suppressor of

Statement

Reference

Scer\GAL4^nub.PU/syd^GLC01419 is a suppressor | partially of wing phenotype of Scer\GAL4^nub.PU, hpo^HMS00006

(Ahmad et al., 2021)

syd^GLC01419/Scer\GAL4^ptc.PU is a suppressor | partially of anterior-posterior compartment boundary of the wing disc phenotype of Scer\GAL4^ptc.PU, yki^UAS.cHa

(Ahmad et al., 2021)

Scer\GAL4^nub.PU/syd^GLC01419 is a suppressor | partially of wing disc phenotype of Scer\GAL4^nub.PU, yki^UAS.cHa

(Ahmad et al., 2021)

Scer\GAL4^hh.PU/syd^GLC01419 is a suppressor | partially of wing disc posterior compartment phenotype of Scer\GAL4^hh.PU, yki^UAS.cHa

(Ahmad et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

43232

y¹ v¹; P{TRiP.GLC01419}attP2/TM3, Sb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

syd^GLC01419

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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