FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\sca5-120
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General Information
Symbol
Dmel\sca5-120
Species
D. melanogaster
Name
FlyBase ID
FBal0282374
Feature type
allele
Associated gene
Dmel\sca
Associated Insertion(s)
P{GawB}sca5-120
Carried in Construct
Also Known As
5-120
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Kaun et al., 2011)
Progenitor genotype
Associated Insertion(s)
P{GawB}sca5-120
Cytology
Description

P{GawB} is inserted 125bp 5' of exon 1 of sca.

(Kaun et al., 2011)
Allele components
Component
Use(s)
Inserted element
P{GawB}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      sca5-120 mutants show conditioned aversion to ethanol when tested 30 minutes after training, although they fail to switch from conditioned aversion to preference. sca5-120 mutants show normal sensitivity to acute ethanol exposure, place-memory performance and olfactory-shock memory performance, indicating that their failure to form associations between odorants and the rewarding effects of ethanol is not a result of a general inability to learn. sca5-120 mutants show normal olfactory acuity and do not show any gross morphological abnormalities of the mushroom body.

      (Kaun et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      sca1

      (Kaun et al., 2011)

      scaBP2

      (Kaun et al., 2011)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      5-120
      (Kaun et al., 2011)
      sca5-120
      (Petruccelli et al., 2018)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)