FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\gbbUAS.cUa
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General Information
Symbol
Dmel\gbbUAS.cUa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Unknown
FlyBase ID
FBal0283047
Feature type
allele
Associated gene
Dmel\gbb
Associated Insertion(s)
Carried in Construct
P{UAS-gbb.U}
Also Known As
UAS-gbb
Key Links
Transgenic product class
wild_type
(FlyBase Curators, 2025-)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(FlyBase Curators, 2025-)
Mutagen
in vitro construct
(FlyBase Curators, 2025-)
Progenitor genotype
Carried in construct
P{UAS-gbb.U}
Cytology
Description

UAS regulatory sequences drive expression of gbb.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
gbb
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expressing gbbUAS.cUa under the control of Scer\GAL4Mhc.Switch.PO (after feeding with RU486) results in supernumerary mature and satellite boutons at the NMJ in third instar larvae.

      (Kim et al., 2019)

      Expression of gbbUAS.cUa under the control of Scer\GAL4A9 causes an increase in the number of wing veins in the adult.

      (Wang et al., 2018)

      Expression of gbbScer\UAS.cUa under the control of Scer\GAL4elav.Switch.PO in the presence of RU486 results in vacuolisation and increased cell death in the brains of 20 day old flies.

      (Nahm et al., 2013)

      Flies expressing gbbScer\UAS.cUa under the control of Scer\GAL4vg.PM show show ectopic wing vein formation.

      (Yu et al., 2013)

      7-day old germaria expressing gbbScer\UAS.cUa via Scer\GAL4hh.PU (with expression controlled via 'UAS-gal80[ts]' and temperature) have normal numbers of germline cell stems (GSCs) and cap cells. However, 63-day old germaria have a significantly greater number of GSCs and cap cells compared to controls, demonstrating increased maintenance rates. They also carry significantly more cysts than controls at this age. BrdU labelling rates are unaffected at young ages in the mutant germaria, but are significantly increased at 63-day old germaria compared to controls.

      (Pan et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      Scer\GAL4A9, gbbUAS.cUa has visible | adult stage phenotype, enhanceable by Scer\GAL4A9/anchorGD3613

      (Wang et al., 2018)
      Suppressed by
      NOT suppressed by
      Statement
      Reference

      Scer\GAL4vg.PM, gbbUAS.cUa has visible phenotype, non-suppressible by Hsap\MTMR4C407S.UAS, Scer\GAL4vg.PM

      (Yu et al., 2013)
      Enhancer of
      Statement
      Reference

      Scer\GAL4A9/gbbUAS.cUa is an enhancer of visible | adult stage phenotype of Scer\GAL4A9, anchorGD3613

      (Wang et al., 2018)
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      Scer\GAL4A9, gbbUAS.cUa has wing vein | increased number phenotype, enhanceable by Scer\GAL4A9/anchorGD3613

      (Wang et al., 2018)
      Suppressed by
      NOT suppressed by
      Statement
      Reference

      Scer\GAL4vg.PM, gbbUAS.cUa has wing vein | ectopic phenotype, non-suppressible by Hsap\MTMR4C407S.UAS, Scer\GAL4vg.PM

      (Yu et al., 2013)
      Enhancer of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of CG3632Scer\UAS.cYa partially suppresses the ectopic wing vein formation seen in flies expressing gbbScer\UAS.cUa under the control of Scer\GAL4vg.PM.

      (Yu et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference

      Co-expression of Hsap\MTMR4Scer\UAS.cYa partially suppresses the ectopic wing vein formation seen in flies expressing gbbScer\UAS.cUa under the control of Scer\GAL4vg.PM.

      Co-expression of Hsap\MTMR4C407S.Scer\UAS does not suppress the ectopic wing vein formation seen in flies expressing gbbScer\UAS.cUa under the control of Scer\GAL4vg.PM.

      (Yu et al., 2013)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      gbbScer\UAS.cUa
      gbbUAS.cUa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Unknown
      Secondary FlyBase IDs
        References (11)