FB2026_02 , released June 18, 2026
Allele: Scer\GAL4Crz.2fa
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General Information
Symbol
Scer\GAL4Crz.2fa
Species
S. cerevisiae
Name
FlyBase ID
FBal0283232
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
P{Crz-GAL4.391}2fa
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Tayler et al., 2012)
Progenitor genotype
Scer\GAL4Crz.391
(Tayler et al., 2012)
Associated Insertion(s)
P{Crz-GAL4.391}2fa
Cytology
Description

Specific insertion of P{Crz-GAL4.391} lacking expression in the abdominal ganglion (presumably due to chromosomal position effects).

(Tayler et al., 2012)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      neuron of adult brain
      (Tayler et al., 2012)
      Additional Information
      Statement
      Reference

      ScerGAL4Crz.2fa drives expression in a few central brain neurons. In contrast to ScerGAL4Crz.391, it does not label the 2 pairs of interneurons in the abdominal male ganglion.

      (Tayler et al., 2012)
       
      Marker for
      Reflects expression of
      Crz
      (Tayler et al., 2012)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Optogenetic activation (using Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus with 650 nm (red) light) of Scer\GAL4Crz.2fa cells does not induce ejaculation in males and does not cause a preference for an illuminated zone over non-illuminated areas, similar to controls; activation in combination with a paired odor does not induce attractive olfactory memory, similar to controls; repeated activation over a few days does not affect preference for ethanol-containing food, compared to controls.

      (Zer-Krispil et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4Crz.2fa
      Name Synonyms
      Secondary FlyBase IDs
        References (4)