FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mblUAS.cLa
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General Information
Symbol
Dmel\mblUAS.cLa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Li
FlyBase ID
FBal0283316
Feature type
allele
Associated gene
Dmel\mbl
Associated Insertion(s)
Carried in Construct
P{UAS-mbl.L}
Key Links
Transgenic product class
cDNA
(Li et al., 2008)
wild_type
(Li et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Li et al., 2008)
wild_type
(Li et al., 2008)
Mutagen
in vitro construct
(Li et al., 2008)
Progenitor genotype
Carried in construct
P{UAS-mbl.L}
Cytology
Description

UAS regulatory sequences drive expression of a cDNA corresponding to the mbl A isoform.

(Li et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
mbl
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing mblScer\UAS.cLa pan-neuronally under the control of Scer\GAL4elav-C155 have a normal pattern of seven photoreceptors per ommatidium.

      (Li et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Phenotype Manifest In
      Enhancer of
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of mblScer\UAS.cLa enhances the reduction in lifespan and photoreceptor loss seen when Hsap\ATXN3tr.Q78.Scer\UAS.T:Ivir\HA1 is expressed pan-neuronally under the control of Scer\GAL4elav-C155. Flies have on average 3.0 photoreceptors per ommatidium, compared to the usual seven.

      (Li et al., 2008)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      mblScer\UAS.cLa
      mblUAS.cLa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Li
      Secondary FlyBase IDs
        References (1)