FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\bru1UASp.mGFP6
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General Information
Symbol
Dmel\bru1UASp.mGFP6
Species
D. melanogaster
Name
FlyBase ID
FBal0284047
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UASp regulatory sequences drive expression of bru1 tagged with mGFP6.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Flies expressing aretScer\UAS.P\T.T:Avic\GFP-m6 under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 show significant defects during oogenesis, with females laying very few eggs or none at all. During oogenesis, each cyst contains 32 germline cells, compared to the 16 seen in wild type. These cysts typically become necrotic in the later stages of oogenesis. If a mature oocyte does form the phenotypes varies, ranging from close to wild type to dramatically defective. Over 85% of embryos are smaller than wild type, and eggs have shortened and irregular dorsal appendages which are frequently fused, suggesting that the eggshells are ventralised. A minor fraction of eggs have the spindle shape and absence of dorsal appendages that are characteristic of strongly ventralised embryos.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
aretScer\UAS.P\T.T:Avic\GFP-m6
bru1Scer\UAS.P\T.T:Avic\GFP-m6
bru1UASp.mGFP6
Name Synonyms
Secondary FlyBase IDs
    References (1)