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General Information
Symbol
Dmel\Ptp61FUAS.m.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0284594
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of the ER-targeted isoform of Ptp61F. The protein is tagged at the N-terminal end with 3 copies of the Tag:MYC epitope.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Ptp61FScer\UAS.m.T:Hsap\MYC under the control of Scer\GAL4GMR.PF does not result in a mutant eye phenotype.

Expression of Ptp61FScer\UAS.m.T:Hsap\MYC under the control of Scer\GAL4dpp.PU has no significant effect on the area of the 1st posterior cell of the wing.

Expression of Ptp61FScer\UAS.m.T:Hsap\MYC under the control of Scer\GAL4GMR.PF does not result in a mutant eye phenotype.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of Ptp61FScer\UAS.m.T:Hsap\MYC partially suppresses the eye overgrowth phenotype caused by expression of InRScer\UAS.cUa under the control of Scer\GAL4GMR.PF.

Co-expression of Ptp61FScer\UAS.m.T:Hsap\MYC partially suppresses the eye overgrowth phenotype caused by expression of InRScer\UAS.cUa under the control of Scer\GAL4GMR.PF.

Co-expression of dockScer\UAS.cRa results in a further reduction in eye overgrowth in flies co-expressing both Ptp61FScer\UAS.m.T:Hsap\MYC and InRScer\UAS.cUa under the control of Scer\GAL4GMR.PF.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Simultaneous co-expression of Ptp61FScer\UAS.m.T:Hsap\MYC and Ptp61FScer\UAS.n.T:Hsap\MYC under the control of Scer\GAL4arm.PU rescues the reduced lifespan of Ptp61FΔ flies. The reduced fecundity of Ptp61FΔ females is also largely rescued.

Expression of Ptp61FScer\UAS.m.T:Hsap\MYC under the control of Scer\GAL4Act.PU fails to rescue the reduced lifespan of Ptp61FΔ flies.

Expression of Ptp61FScer\UAS.m.T:Hsap\MYC under the control of Scer\GAL4arm.PU partially rescues the reduced fecundity of Ptp61FΔ females.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Ptp61FScer\UAS.m.T:Hsap\MYC
Ptp61FUAS.m.Tag:MYC
Name Synonyms
Secondary FlyBase IDs
    References (2)