FlyBase Allele Report: Dmel\lncRNA:CRG[Δ1877]

General Information

Symbol

Dmel\lncRNA:CRG^Δ1877

Species

D. melanogaster

Name

FlyBase ID

FBal0285195

Feature type

allele

Associated gene

Dmel\lncRNA:CRG

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

amorphic allele - molecular evidence

Mutagen

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Li et al., 2012)

Mutagen

ends-in gene targeting

(Li et al., 2012)

FLPase

(Li et al., 2012)

I-SceI

(Li et al., 2012)

I-CreI

(Li et al., 2012)

Progenitor genotype

Cytology

Description

Deletion of 1877bp of the CRG gene.

(Li et al., 2012)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | adult stage

(Li et al., 2012)

fertile

(Li et al., 2012)

viable

(Li et al., 2012)

Phenotype Manifest In

Detailed Description

Statement

Reference

Mutants are defective in locomotor activity and climbing activity when tested with the Buridan's paradigm and a negative geotaxis assay, respectively.

(Li et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

lncRNA:CRG^Δ1877 has abnormal locomotor behavior | adult stage phenotype, suppressible by Scer\GAL4^elav.PU/CASK^UAS.cZa

(Li et al., 2012)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Expression of CASK^Scer\UAS.cZa under the control of Scer\GAL4^elav.PU rescues the locomotor activity and climbing defects of CRG^Δ1877 flies.

(Li et al., 2012)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

lncRNA:CRG^Δ1877 is rescued by Scer\GAL4^elav.PU/lncRNA:CRG^UAS.GFP

(Li et al., 2012)

Not rescued by

lncRNA:CRG^Δ1877 is not rescued by lncRNA:CRG^UAS.GFP/Scer\GAL4^G7

(Li et al., 2012)

lncRNA:CRG^Δ1877 is not rescued by Scer\GAL4^RapGAP1-OK6/lncRNA:CRG^UAS.GFP

(Li et al., 2012)

Comments

Expression of CRG^{Scer\UAS.T:Avic\GFP} under the control of Scer\GAL4^elav.PU rescues the locomotor activity and climbing defects of CRG^Δ1877 flies. Expression under the control of either Scer\GAL4^G7 or Scer\GAL4^Rapgap1-OK6 does not rescue the behavioural defects.

(Li et al., 2012)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CRG^Δ1877

(Li et al., 2012)

lncRNA:CRG^Δ1877

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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