FB2026_02 , released June 18, 2026
Allele: Bper\ptxAtetO.cCa
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General Information
Symbol
Bper\ptxAtetO.cCa
Species
B. pertussis
Name
Tn10 tetracycline operator construct a of Chatterjee
FlyBase ID
FBal0285561
Feature type
allele
Associated gene
Bper\ptxA
Associated Insertion(s)
Carried in Construct
P{tetO-PTX.C}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Chatterjee et al., 2009)
Progenitor genotype
Carried in construct
P{tetO-PTX.C}
Cytology
Description

tetO regulates expression of Bper\ptxA.

(Chatterjee et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
tetO
Encoded product / tool
Bper\ptxA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Conditional expression of Bper\ptxATn10\tetO.cCa in mature virgin females under the control of the doxycyclin-inducible Tn10\tetRM2.alt.Scer\UAS.T:Hsim\VP16 in the eye using Scer\GAL4GMR.PF does not alter their post-mating behaviour.

      Conditional expression of Bper\ptxATn10\tetO.cCa in mature virgin females under the control of the doxycyclin-inducible Tn10\tetRM2.alt.Scer\UAS.T:Hsim\VP16 in Scer\GAL4ppk.PG and Scer\GAL4dsx.KI patterns inhibits their response to injected SP, resulting in mating and egg laying similar to virgin females.

      Conditional expression of Bper\ptxATn10\tetO.cCa in mature virgin females under the control of the doxycyclin-inducible Tn10\tetRM2.alt.Scer\UAS.T:Hsim\VP16 in Scer\GAL4fru.P1.D patterns inhibits egg laying post-mating, but these females, similarly to controls, still reduce receptivity in response to mating.

      (Haussmann et al., 2013)

      In the presence of Scer\GAL4Orco.2.642.T:Hsim\VP22, Tn10\tetRM2.alt.Scer\UAS.T:Hsim\VP16, addition of doxycycline results in suppression of electroantennogram amplitude in response to 10[-4] ethyl acetate by ~40%.

      (Chatterjee et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Co-expression of GαoScer\UAS.Pi, a PTX-insensitive Gαo, rescues the action of Scer\GAL4Orco.2.642.T:Hsim\VP22, Tn10\tetRM2.alt.Scer\UAS.T:Hsim\VP16-mediated expression of Bper\ptxATn10\tetO.cCa on endogenous Gαo - addition of doxycycline no longer reduces electroantennogram amplitude in response to 10[-4] ethyl acetate.

      (Chatterjee et al., 2009)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Bper\ptxATn10\tetO.cCa
      Bper\ptxAtetO.cCa
      Name Synonyms
      Tn10 tetracycline operator construct a of Chatterjee
      Secondary FlyBase IDs
        References (2)