FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\plumECD.UAS.Tag:M(mCd8a),Tag:FLAG
Open Close
General Information
Symbol
Dmel\plumECD.UAS.Tag:M(mCd8a),Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0288236
Feature type
allele
Associated gene
Dmel\plum
Associated Insertion(s)
Carried in Construct
P{UAS-plum.ECD.mCD8.TM.Flag}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Yu et al., 2013)
Progenitor genotype
Carried in construct
P{UAS-plum.ECD.mCD8.TM.Flag}
Cytology
Description

UAS regulatory sequences drive expression of plum in which the transmembrane and cytoplasmic domains have been replaced with the Mmus\Cd8a transmembrane domain. The protein is tagged with Tag:FLAG.

(Yu et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
plum
Tagged with
Tag:FLAG
Tag:M(mCd8a)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expressing plumECD.UAS.Tag:M(mCd8a),Tag:FLAG under the control of Scer\GAL4repo.PU, but not Scer\GAL4elav-C155, leads to adult mushroom body β-axons over-extending beyond the midline in some cases.

      Expressing plumECD.UAS.Tag:M(mCd8a),Tag:FLAG under the control of Scer\GAL4ey-OK107 does not induce adult β-lobe retraction.

      (Marmor-Kollet et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      plumECD.UAS.Tag:M(mCd8a),Tag:FLAG/Scer\GAL4Tab2-201Y rescues plumΔ1

      (Yu et al., 2013)
      Fails to rescue

      plumECD.UAS.Tag:M(mCd8a),Tag:FLAG/Scer\GAL4GMR44E04 fails to rescue plumΔ1

      (Marmor-Kollet et al., 2019)
      Comments

      Expression of plumECD.Scer\UAS.T:Mmus\Cd8a,T:Zzzz\FLAG under the control of Scer\GAL4Tab2-201Y rescues the γ neuron pruning defects seen in plumΔ1 mushroom body neuroblast clones.

      (Yu et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      PlumECD:mCD8TM
      (Yu et al., 2013)
      plumECD.Scer\UAS.T:Mmus\Cd8a,T:Zzzz\FLAG
      plumECD.UAS.Tag:M(mCd8a),Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (3)