FlyBase Allele Report: Dmel\alph[S-331.GMR]

General Information

Symbol

Dmel\alph^S-331.GMR

Species

D. melanogaster

Name

FlyBase ID

FBal0288396

Feature type

allele

Associated gene

Dmel\alph

Associated Insertion(s)

Carried in Construct

P{GMR-alph.S-331}

Key Links

Transgenic product class

missense_variant

(Baril et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

missense_variant

(Baril et al., 2009)

Mutagen

in vitro construct

(Baril et al., 2009)

Progenitor genotype

Carried in construct

P{GMR-alph.S-331}

Cytology

Description

GMR regulatory sequences drive expression of an alph^S-331 mutant cDNA (derived from the alph-RB transcript).

(Baril et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

GMR

engineered transcription regulatory region

Encoded product / tool

alph

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

alph^S-331.GMR/alph[+] is an enhancer of eye phenotype of Rac1^GMR.PN

(Baril et al., 2009)

NOT Enhancer of

Statement

Reference

alph^S-331.GMR/alph[+] is a non-enhancer of eye phenotype of hep^{CA.sev.Tag:MYC}

(Baril et al., 2009)

alph^S-331.GMR/alph[+] is a non-enhancer of eye phenotype of lic^{CA.sev.Tag:MYC}

(Baril et al., 2009)

NOT Suppressor of

Statement

Reference

alph^S-331.GMR/alph[+] is a non-suppressor of eye phenotype of hep^{CA.sev.Tag:MYC}

(Baril et al., 2009)

alph^S-331.GMR/alph[+] is a non-suppressor of eye phenotype of lic^{CA.sev.Tag:MYC}

(Baril et al., 2009)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of alph^S-331.GMR is not only unable to suppress the Rac1^GMR.PN rough eye, but also slightly enhances this phenotype.

(Baril et al., 2009)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

alph^S-331.GMR

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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