FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\HtrA2RNAi.UAS.cYa
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General Information
Symbol
Dmel\HtrA2RNAi.UAS.cYa
Species
D. melanogaster
Name
FlyBase ID
FBal0288461
Feature type
allele
Associated gene
Dmel\HtrA2
Associated Insertion(s)
Carried in Construct
P{UAS-HtrA2.RNAi.Y}
Key Links
Transgenic product class
RNAi_reagent
(Yun et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Yun et al., 2008)
Mutagen
in vitro construct
(Yun et al., 2008)
Progenitor genotype
HtrA2UAS.cYa
(Yun et al., 2008)
Carried in construct
P{UAS-HtrA2.RNAi.Y}
Cytology
Description

UAS regulatory sequences drive expression of sequences targeting the HtrA2 coding region.

(Yun et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
HtrA2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      HtrA2RNAi.UAS.cYa, Scer\GAL4GMR.PF is a non-suppressor of visible phenotype of Pink1UAS.cCa, Scer\GAL4GMR.PF

      (Yun et al., 2008)
      Phenotype Manifest In
      NOT Enhancer of
      NOT Suppressor of
      Statement
      Reference

      HtrA2RNAi.UAS.cYa, Scer\GAL4GMR.PF is a non-suppressor of eye phenotype of Pink1UAS.cCa, Scer\GAL4GMR.PF

      (Yun et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of HtrA2dsRNA.Scer\UAS.cYa fails to suppress the rough eye phenotype seen when Pink1Scer\UAS.cCa is expressed under the control of Scer\GAL4GMR.PF at 29[o]C.

      Expression of HtrA2dsRNA.Scer\UAS.cYa under the control of Scer\GAL4Mef2.PR does not enhance the mitochondrial morphology defects seen in Pink15 mutant indirect flight muscles.

      (Yun et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      HtrA2RNAi.UAS.cYa
      HtrA2dsRNA.Scer\UAS.cYa
      HtrA2dsRNA.UAS.cYa
      Name Synonyms
      Secondary FlyBase IDs
        References (2)