FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\daΔTADs.UAS.Tag:MYC
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General Information
Symbol
Dmel\daΔTADs.UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0290361
Feature type
allele
Associated gene
Dmel\da
Associated Insertion(s)
Carried in Construct
P{UAS-da.ΔTADs}
Key Links
Transgenic product class
inframe_deletion
(Zarifi et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Zarifi et al., 2012)
Mutagen
in vitro construct
(Zarifi et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-da.ΔTADs}
Cytology
Description

UASt regulatory sequences drive expression of da lacking the both the AD1 and LH transcription activation domains (amino acids 1-414 are deleted). The protein is tagged with 3 copies of Tag:MYC.

(Zarifi et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
da
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of daΔTADs.Scer\UAS.T:Hsap\MYC under the control of either Scer\GAL4sca-C253 or Scer\GAL4pnr-MD237 results in the loss of many bristles in the notum.

      Clones of cells in the antennal disc expressing daΔTADs.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4Act.PU do not form sensory precursor cells.

      Some cells within clones in the eye disc expressing daΔTADs.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4Act.PU can form R8 photoreceptor cells, but most R8 cells form in adjacent wild-type cells.

      Photoreceptor R8 cells are not seen in clones in the eye disc expressing daΔTADs.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4Act.PU in a da10 background.

      (Zarifi et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of daΔTADs.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4sca-C253 is unable to induce sensory organ precursor cells (SOP) in the wing disc in a Df(1)sc10-1 background, save the occasional SOP escaper.

      Co-expression of sc1-260.Scer\UAS and daΔTADs.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4sca-C253 is unable to induce SOP cells in the wing disc in a Df(1)sc10-1 background, save the occasional SOP escaper.

      (Zarifi et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      daΔTADs.UAS.Tag:MYC/Scer\GAL4Tub.PU fails to rescue da10

      (Zarifi et al., 2012)
      Comments

      Expression of daΔTADs.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4tub.PU in da10 clones in the wing disc fails to rescue sensory organ precursor cell formation.

      (Zarifi et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      daΔTADs.Scer\UAS.T:Hsap\MYC
      daΔTADs.UAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)