FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\fzrA
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General Information
Symbol
Dmel\fzrA
Species
D. melanogaster
Name
FlyBase ID
FBal0291326
Feature type
allele
Associated gene
Dmel\fzr
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Manivannan et al., 2022)
Mutagen
ethyl methanesulfonate
(Graves et al., 2020, Yamamoto et al., 2013-)
Progenitor genotype
Cytology
Description

Splice site mutation: c592+1G>A.

(Manivannan et al., 2022)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
X:4,676,253..4,676,253 [-]
Nucleotide change:

G4676253A

Comment:

Nucleotide substitution: GT changed to AT in the splice donor. Reported as c592+1G>A in fzr-RA.

(Manivannan et al., 2022)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      fzrA has lethal | recessive phenotype, suppressible by Dp(1;3)DC472

      (Manivannan et al., 2022)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      XAWL051
      (Graves et al., 2020)
      XE49A
      (Graves et al., 2020)
      fzrA
      (Manivannan et al., 2022, Graves et al., 2020, Ly and Wang, 2020)
      fzrrapA
      (Weber and Mlodzik, 2017)
      rapA
      (Yamamoto et al., 2013-)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)