FlyBase Allele Report: Dmel\Liprin-α[HMC03183]

General Information

Symbol

Dmel\Liprin-α^HMC03183

Species

D. melanogaster

Name

FlyBase ID

FBal0292360

Feature type

allele

Associated gene

Dmel\Liprin-α

Associated Insertion(s)

Carried in Construct

P{TRiP.HMC03183}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMC03183}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMC03183

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates high grade glioma

modeled by Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, btl::Egfr^λ.UAS

(Losada-Pérez et al., 2022)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Liprin-α^HMC03183, Scer\GAL4^GMR.long is a suppressor of abnormal neuroanatomy phenotype of Scer\GAL4^GMR.long, side-IV^{ΔCyto.UAS.Tag:V5}

(Osaka et al., 2024)

Liprin-α^HMC03183, Scer\GAL4^GMR.long is a suppressor of abnormal neuroanatomy phenotype of Scer\GAL4^GMR.long, side-IV^UAS.cOa

(Osaka et al., 2024)

Phenotype Manifest In

Suppressor of

Statement

Reference

Liprin-α^HMC03183, Scer\GAL4^GMR.long is a suppressor of photoreceptor cell R7 phenotype of Scer\GAL4^GMR.long, side-IV^{ΔCyto.UAS.Tag:V5}

(Osaka et al., 2024)

Liprin-α^HMC03183, Scer\GAL4^GMR.long is a suppressor of medulla phenotype of Scer\GAL4^GMR.long, side-IV^{ΔCyto.UAS.Tag:V5}

(Osaka et al., 2024)

Liprin-α^HMC03183, Scer\GAL4^GMR.long is a suppressor of synapse | ectopic phenotype of Scer\GAL4^GMR.long, side-IV^{ΔCyto.UAS.Tag:V5}

(Osaka et al., 2024)

Liprin-α^HMC03183, Scer\GAL4^GMR.long is a suppressor of synapse | ectopic phenotype of Scer\GAL4^GMR.long, side-IV^UAS.cOa

(Osaka et al., 2024)

Liprin-α^HMC03183, Scer\GAL4^GMR.long is a suppressor of photoreceptor cell R7 phenotype of Scer\GAL4^GMR.long, side-IV^UAS.cOa

(Osaka et al., 2024)

Liprin-α^HMC03183, Scer\GAL4^GMR.long is a suppressor of medulla phenotype of Scer\GAL4^GMR.long, side-IV^UAS.cOa

(Osaka et al., 2024)

Liprin-α^HMC03183, Scer\GAL4^GMR.long is a suppressor of axon phenotype of Scer\GAL4^GMR.long, side-IV^UAS.cOa

(Osaka et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

53868

y¹ v¹; P{TRiP.HMC03183}attP40

NIG-Fly

HMC03183

y¹ v¹; P{TRiP.HMC03183}attP40

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Liprin-α^HMC03183

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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