FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Ecol\lexALHG.dpp
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General Information
Symbol
Ecol\lexALHG.dpp
Species
E. coli
Name
FlyBase ID
FBal0295122
Feature type
allele
Associated gene
Ecol\lexA
Associated Insertion(s)
Carried in Construct
M{dpp-LHG}
Also Known As
dpp-LHG, dpp-lexA
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Yagi et al., 2010)
Progenitor genotype
Carried in construct
M{dpp-LHG}
Cytology
Description

dpp imaginal disc enhancer sequences drive expression of the 'LHG' lexA::GAD driver, which is composed of Ecol\lexA (providing DNA binding specificity) fused with the hinge region and the transcriptional activator domain of Scer\GAL4.

(Yagi et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
dpp
Encoded product / tool
lexA::GAD
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      wandering third instar larval stage
      anterior-posterior compartment boundary of the wing disc
      (Yagi et al., 2010)
      adult stage | male
      hub cell
      (Inaba et al., 2015)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      dpp
      (Inaba et al., 2015, Yagi et al., 2010)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of M{dpp-LHG}ZH-86Fb results in elevated apoptosis in the wing imaginal disc.

      (Yagi et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ecol\lexALHG.dpp
      Ecol\lexAdpp.T:Scer\GAL4-H,T:Scer\GAL4-GAD
      Name Synonyms
      Secondary FlyBase IDs
        References (8)