FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Hsap\TRAIPnopo.PW
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General Information
Symbol
Hsap\TRAIPnopo.PW
Species
H. sapiens
Name
no poles promoter construct of Wallace
FlyBase ID
FBal0296080
Feature type
allele
Associated gene
Hsap\TRAIP
Associated Insertion(s)
Carried in Construct
P{nopo-TRAIP.cDNA}
Key Links
Transgenic product class
cDNA
(Wallace et al., 2014)
wild_type
(Wallace et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Wallace et al., 2014)
wild_type
(Wallace et al., 2014)
Mutagen
in vitro construct
(Wallace et al., 2014)
Progenitor genotype
nopo+t3.8
(Wallace et al., 2014)
Carried in construct
P{nopo-TRAIP.cDNA}
Cytology
Description

The genomic sequence between the 5' and 3' UTRs in nopo+t3.8 has been replaced with cDNA sequence encoding the Hsap\TRAIP open reading frame, resulting in Hsap\TRAIP expressed under the control of endogenous nopo regulatory sequences.

(Wallace et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
nopo
Encoded product / tool
Hsap\TRAIP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Hsap\TRAIPnopo.PW is a suppressor | partially of mitotic spindle | maternal effect phenotype of nopoExc142

      (Wallace et al., 2014)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Hsap\TRAIPnopo.PW rescues the hatch rate of embryos derived from nopoExc142 females from 0% to 83%, and the frequency of embryos with abnormal spindle morphology is reduced from 94% to 14%.

      (Wallace et al., 2014)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Hsap\TRAIPnopo.PW
      Name Synonyms
      no poles promoter construct of Wallace
      Secondary FlyBase IDs
        References (1)