FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\BxA523
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General Information
Symbol
Dmel\BxA523
Species
D. melanogaster
Name
FlyBase ID
FBal0300934
Feature type
allele
Associated gene
Dmel\Bx
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
    Nature of the Allele
    Allele class

    loss of function allele

    (Ren et al., 2014)
    Mutagen
    Progenitor genotype
    Cytology
    Description

    An early termination codon (TAG) in the coding sequence of Bx.

    (Ren et al., 2014)

    Amino acid replacement: ??term.

    (Ren et al., 2014)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        The abdomen of adult mutants is bloated and the crop is enlarged. This is a result of progressive food accumulation in the crop and is apparent one day after eclosion. The enlarged crop phenotype is not due to progressive excessive food intake, but rather correlated with a significant reduction in defecation indicating a defect in gastric emptying from the crop into the midgut. The muscles ensheathing the crop differentiate and pattern normally.

        BxA523/BxJ wings are small and lack areas of wing margin. This phenotype is less severe than BxJ wings and is similar to BxJ /+ wings.

        BxA523/Bx2 wings appear wild type. This phenotype is less severe than Bx2 wings and is similar to Bx2 /+ wings.

        (Ren et al., 2014)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        A523
        (Ren et al., 2014)
        BxA523
        Name Synonyms
        Secondary FlyBase IDs
          References (1)