FlyBase Allele Report: Dmel\bsk[HMS04479]

General Information

Symbol

Dmel\bsk^HMS04479

Species

D. melanogaster

Name

FlyBase ID

FBal0301039

Feature type

allele

Associated gene

Dmel\bsk

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS04479}

Also Known As

HMS04479, UAS-JNK-RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS04479}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS04479

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates fragile X syndrome

modeled by Fmr1^Δ50M

(Russo and DiAntonio, 2019)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | adult stage, with Scer\GAL4^GMR71G10

(Meltzer et al., 2019)

abnormal neuroanatomy | P-stage, with Scer\GAL4^ppk.PU

(Zheng et al., 2025)

female semi-sterile, with Scer\GAL4^{VP16.mat.αTub67C}

(Sopko et al., 2014)

Phenotype Manifest In

axon | adult stage, with Scer\GAL4^GMR71G10

(Meltzer et al., 2019)

dendrite | P-stage, with Scer\GAL4^ppk.PU

(Zheng et al., 2025)

embryo | maternal effect, with Scer\GAL4^{VP16.mat.αTub67C}

(Sopko et al., 2014)

gamma Kenyon cell | adult stage, with Scer\GAL4^GMR71G10

(Meltzer et al., 2019)

larval multidendritic class IV neuron | P-stage, with Scer\GAL4^ppk.PU

(Zheng et al., 2025)

Detailed Description

Statement

Reference

Expressing bsk^HMS04479 under the control of Scer\GAL4^GMR71G10 leads to frequent mushroom body gamma neuron pruning defects.

(Meltzer et al., 2019)

Females heterozygous for bsk^HMS04479 and Scer\GAL4^{mat.αTub67C.T:Hsim\VP16} crossed to bsk^HMS04479 males results in: 61% hatching; egg/embryonic phenotype: dorsal closure defects; maternal effect.

(Sopko et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^elav.PU/bsk^HMS04479 is a suppressor of abnormal neuroanatomy | third instar larval stage phenotype of Fmr1^Δ50M

(Russo and DiAntonio, 2019)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^nanos.PG/bsk^HMS04479 is a suppressor of egg chamber | absent phenotype of Dyro^Δ6

(Shima et al., 2025)

Scer\GAL4^elav.PU/bsk^HMS04479 is a suppressor of NMJ bouton | increased number | third instar larval stage phenotype of Fmr1^Δ50M

(Russo and DiAntonio, 2019)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

57035

y¹ sc^* v¹ sev²¹; P{TRiP.HMS04479}attP40

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

basket^dsRNA

(Winkler et al., 2021)

bsk^HMS04479

Name Synonyms

Secondary FlyBase IDs

References (12)

Report Sections

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