FB2026_02 , released June 18, 2026
Allele: Dmel\nSybUAS.Ubi.slowFT
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General Information
Symbol
Dmel\nSybUAS.Ubi.slowFT
Species
D. melanogaster
Name
FlyBase ID
FBal0301191
Feature type
allele
Associated gene
Dmel\nSyb
Associated Insertion(s)
Carried in Construct
PBac{UAS-Ub-FT-nSyb}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Fernandes et al., 2014)
Progenitor genotype
Carried in construct
PBac{UAS-Ub-FT-nSyb}
Cytology
Description

UAS regulatory sequences drive expression of a fusion protein consisting of amino acid residues 1-74 of RpL40, a Gln-Gln-Ser-Arg spacer, slowFT (a fluorescent timer protein that changes from blue to red emission over time, allowing protein turnover to be analysed) and the nSyb coding region. The RpL40 portion encodes ubiquitin (minus the C-terminal Gly residues, to prevent its removal by deubiquitinases), which targets the fusion protein for degradation.

(Fernandes et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
nSyb
Tagged with
slowFT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      nSybScer\UAS.Ubi.T:Disc\RFP-slowFT
      nSybUAS.Ubi.slowFT
      Name Synonyms
      Secondary FlyBase IDs
        References (1)