FlyBase Allele Report: Dmel\Dhx15[GS11266]

General Information

Symbol

Dmel\Dhx15^GS11266

Species

D. melanogaster

Name

FlyBase ID

FBal0301224

Feature type

allele

Associated gene

Dmel\Dhx15

Associated Insertion(s)

P{GSV6}Dhx15^GS11266

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{GSV6}Dhx15^GS11266

Cytology

Description

P{GSV6} insertion 236bp upstream of Dhx15.

(Mosallanejad et al., 2014)

Allele components

Component

Use(s)

Inserted element

P{GSV6}

misexpression element

Regulatory region(s)

UASt

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:7,387,450..7,387,450

(Mosallanejad et al., 2014)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal body color, with Scer\GAL4^pnr-MD237

(Mosallanejad et al., 2014)

Phenotype Manifest In

adult cuticle, with Scer\GAL4^pnr-MD237

(Mosallanejad et al., 2014)

Detailed Description

Statement

Reference

Adults expressing Dhx15^GS11266 under the control of Scer\GAL4^pnr-MD237 show melanin accumulation in the thorax. This melanisation is abolished by co-expression of Dhx15^NIG.11107R.

(Mosallanejad et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Dhx15^GS11266, Scer\GAL4^pnr-MD237 has abnormal body color phenotype, non-enhanceable by Ask1^RNAi.UAS, Scer\GAL4^pnr-MD237

(Mosallanejad et al., 2014)

Suppressed by

Statement

Reference

Dhx15^GS11266, Scer\GAL4^pnr-MD237 has abnormal body color phenotype, suppressible | partially by p38a^DN.UAS, Scer\GAL4^pnr-MD237

(Mosallanejad et al., 2014)

NOT suppressed by

Statement

Reference

Dhx15^GS11266, Scer\GAL4^pnr-MD237 has abnormal body color phenotype, non-suppressible by Ask1^RNAi.UAS, Scer\GAL4^pnr-MD237

(Mosallanejad et al., 2014)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Dhx15^GS11266, Scer\GAL4^pnr-MD237 has adult cuticle phenotype, non-enhanceable by Ask1^RNAi.UAS, Scer\GAL4^pnr-MD237

(Mosallanejad et al., 2014)

Suppressed by

Statement

Reference

Dhx15^GS11266, Scer\GAL4^pnr-MD237 has adult cuticle phenotype, suppressible | partially by p38a^DN.UAS, Scer\GAL4^pnr-MD237

(Mosallanejad et al., 2014)

NOT suppressed by

Statement

Reference

Dhx15^GS11266, Scer\GAL4^pnr-MD237 has adult cuticle phenotype, non-suppressible by Ask1^RNAi.UAS, Scer\GAL4^pnr-MD237

(Mosallanejad et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of p38a^DN.Scer\UAS partially suppresses the melanisation of the thorax seen in adults expressing Dhx15^GS11266 under the control of Scer\GAL4^pnr-MD237.

Co-expression of Pk92B^{dsRNA.Scer\UAS} has no effect on the melanisation of the thorax seen in adults expressing Dhx15^GS11266 under the control of Scer\GAL4^pnr-MD237.

(Mosallanejad et al., 2014)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Dhx15^GS11266

GS11266

(Mosallanejad et al., 2014)

kuma2

(Mosallanejad et al., 2014)

Name Synonyms

key upswing in melanin accumulation 2

(Mosallanejad et al., 2014)

Secondary FlyBase IDs

References (1)

Report Sections

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