FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\rebUAS.cMa
Open Close
General Information
Symbol
Dmel\rebUAS.cMa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Moussian
FlyBase ID
FBal0302994
Feature type
allele
Associated gene
Dmel\reb
Associated Insertion(s)
Carried in Construct
P{UAS-reb.M}
Key Links
Transgenic product class
genomic_DNA
(Moussian et al., 2015)
wild_type
(Moussian et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Moussian et al., 2015)
wild_type
(Moussian et al., 2015)
Mutagen
in vitro construct
(Moussian et al., 2015)
Progenitor genotype
Carried in construct
P{UAS-reb.M}
Cytology
Description

UAS regulates expression of genomic reb DNA.

(Moussian et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
reb
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Scer\GAL4btl.PU-mediated co-expression of kkvScer\UAS.T:Avic\GFP and rebScer\UAS.cMa results in early chitin accumulation in the trachea and results in tracheal branches becoming short, very straight and generally unfused. There are defects in tracheal cell shape and cell intercalation. Furthermore, chitin is also deposited in tissues where it does not normally accumulate, including the midline and the proventriculus.

      Scer\GAL4fkh.PU-mediated co-expression of kkvScer\UAS.T:Avic\GFP and rebScer\UAS.cMa results in chitin accumulation in the salivary glands, causing improper invagination/extension.

      Scer\GAL4ap.PU-mediated co-expression of kkvScer\UAS.T:Avic\GFP and rebScer\UAS.cMa results in apical accumulation of chitin between the peripodial membrane and the epithelia, leading to strong morphogenetic defects in the adult wing and notum.

      Scer\GAL448Y-mediated co-expression of kkvScer\UAS.T:Avic\GFP and rebScer\UAS.cMa does not result in extracellular chitin deposition in mesodermal/endodermal tissues.

      (Moussian et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      rebUAS.cMa/Scer\GAL4btl.PU rescues Df(2R)BSC879/Df(2R)ED2247

      (Moussian et al., 2015)
      Comments

      Scer\GAL4btl.PU-mediated expression of rebScer\UAS.cMa fully rescues the aberrant tracheal chitin filament defects of Df(2R)BSC879/Df(2R)ED2247 embryos.

      (Moussian et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      rebScer\UAS.cMa
      rebUAS.cMa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Moussian
      Secondary FlyBase IDs
        References (1)