FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Gr64fLEXA
Open Close
General Information
Symbol
Dmel\Gr64fLEXA
Species
D. melanogaster
Name
FlyBase ID
FBal0304291
Feature type
allele
Associated gene
Dmel\Gr64f
Associated Insertion(s)
TI{lexA::VP16}Gr64fLEXA
Carried in Construct
Also Known As
Gr64f-LexA
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Yavuz et al., 2014)
Mutagen
gene targeting by homologous recombination
(Fujii et al., 2015)
Progenitor genotype
Associated Insertion(s)
TI{lexA::VP16}Gr64fLEXA
Cytology
Description

The Gr64f coding sequence has been replaced with sequence encoding a lexA::VP16 driver.

(Fujii et al., 2015)

The Gr64f coding sequence has been replaced with sequence encoding a lexA::VP16 driver. A single loxP site is also present downstream of the inserted driver sequence.

(Yavuz et al., 2014)
Allele components
Component
Use(s)
Inserted element
TI{lexA::VP16}
Encoded product / tool
lexA::VP16
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
3L:4,035,800..4,037,689 [+]
Comment:

The Gr64f coding sequence has been replaced with sequence encoding a lexA::VP16 driver. A single loxP site is also present downstream of the inserted driver sequence. Position of deletion endpoints on reference sequence determined from reported primer sequences.

(Yavuz et al., 2014)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Gr64fLEXA homozygous, but not heterozygous, mutant adult females have a significant increase in preference for softer 100 mM sucrose-containing, but not plain, agarose for egg laying, compared to controls; mutant females also have a significant reduction in preference for 100 mM sucrose-containing (rather than plain) agarose for egg laying, compared to controls.

      (Wu et al., 2019)

      Homozygous Gr64fLEXA mutant flies exhibit a reduced proboscis extension response to arabinose, glucose and trehalose upon stimulation of the tarsal taste sensilla. The responses to arabinose, glucose and fructose are reduced upon stimulation of the labial sensilla.

      (Fujii et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      Df(3L)ΔGr64/Gr64fLEXA, Gr5a[+]/Gr5aLEXA, Gr61a1 has abnormal oviposition | chemical conditional phenotype

      (Wu et al., 2019)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Adult females with Gr5aLEXA/+, Gr61a1/+ and Gr64fLEXA/Df(3L)ΔGr64, have a significant increase in preference for softer 100 mM sucrose-containing, but not plain, agarose for egg laying, compared to controls; these mutants also have a significant reduction in preference for 100 mM sucrose-containing (rather than plain) agarose for egg laying, compared to controls.

      (Wu et al., 2019)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      References (11)