FlyBase Allele Report: Dmel\ap[R]

General Information

Symbol

Dmel\ap^R

Species

D. melanogaster

Name

FlyBase ID

FBal0304951

Feature type

allele

Associated gene

Dmel\ap

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

neomorphic allele - genetic evidence

Mutagen

phiC31 integrase

Nature of the Allele

Allele class

neomorphic allele - genetic evidence

(Bieli et al., 2015)

Mutagen

phiC31 integrase

(Bieli et al., 2015)

Progenitor genotype

ap^attPΔEnh

(Bieli et al., 2015)

Cytology

Description

An ap-R upstream regulatory element is inserted into the attP site in ap^attPΔEnh.

(Bieli et al., 2015)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible (with ap^DG3)

(Bieli et al., 2015)

visible | dominant

(Bieli et al., 2015)

Phenotype Manifest In

alar lobe (with ap^DG3)

(Bieli et al., 2015)

wing blade

(Bieli et al., 2015)

wing hinge (with ap^DG3)

(Bieli et al., 2015)

wing margin (with ap^DG3)

(Bieli et al., 2015)

Detailed Description

Statement

Reference

Most of the wing margin, the alula and the hinge region are poorly formed in ap^R/ap^DG3 mutants.

A small proportion of homozygous ap^R flies display a small notch in the tip region of the wing.

(Bieli et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

ap^R

ap^apR

(Bieli et al., 2015)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

Open Close