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General Information
Symbol
Dmel\kirrerP298-G4
Species
D. melanogaster
Name
FlyBase ID
FBal0305277
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
rP298-GAL4, rp298gal4, duf-Gal4, rp298.gal4
Key Links
Allele class
Mutagen
    Nature of the Allele
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Insertion components
    P{GawB}kirrerP298-G4
    Product class / Tool use(s)
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    kirrerP298 zygotic mutant embryos exhibit myoblast fusion defects. In contrast to the round and dense morphology seen in wild type, the F-actin enriched-structures between unfused fusion-competent myoblasts and miniature myotubes are irregularly shaped and exhibit abnormally long protrusions.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Enhanced by
    Statement
    Reference

    kirrerP298-G4 has myoblast phenotype, enhanceable by Rho172O

    kirrerP298-G4 has myoblast phenotype, enhanceable by zip1

    Suppressed by
    Statement
    Reference
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    Rho172O enhances the myoblast fusion defects seen in kirrerP298 mutant embryos.

    zip1 enhances the myoblast fusion defects seen in kirrerP298 mutant embryos. In contrast to the round and dense morphology seen in wild type, the F-actin enriched-structures between unfused fusion-competent myoblasts and miniature myotubes are irregularly shaped and exhibit abnormally long protrusions.

    Expression of sqhE21.T:Zzzz\FLAG partially suppresses the myoblast fusion defects seen in kirrerP298 Rho172O mutant embryos, returning fusion to the level of kirrerP298 mutants alone.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (2)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    kirrerP298-G4
    kirrerP298
    Name Synonyms
    Secondary FlyBase IDs
      References (1)