FB2026_02 , released June 18, 2026
Allele: Scer\GAL4DBD.VT007068
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General Information
Symbol
Scer\GAL4DBD.VT007068
Species
S. cerevisiae
Name
FlyBase ID
FBal0316906
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{VT007068-GAL4.DBD}
Also Known As
VT7068-GAL4DBD, VT007068-ZpGAL4DBD
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Rubin Laboratory at Janelia Farm, 2017, Feng et al., 2014)
Progenitor genotype
Carried in construct
P{VT007068-GAL4.DBD}
Cytology
Description

The VT007068 enhancer fragment followed by the Drosophila synthetic core promoter (DSCP) is fused upstream of the GAL4(DBD)::Zip- hemidriver (component of the 'Split GAL4' system, contains the GAL4 DNA-binding domain).

(Rubin Laboratory at Janelia Farm, 2017)
Allele components
Component
Use(s)
Regulatory region(s)
VT007068
Encoded product / tool
GAL4(DBD)::Zip-
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      adult sex peptide abdominal ganglion neuron | subset

      Comment: when combined with P{VT050405-p65.AD} (combination referred to as 'SAG-GAL4')

      (Jang et al., 2017)
      adult sex peptide abdominal ganglion neuron

      Comment: when combined with P{VT050405-p65.AD} (combination referred to as 'SAG-SS')

      when combined with P{VT050405-p65.AD} (combination referred to as 'SAG1-GAL4')

      when combined with P{VT050405-p65.AD} (combination referred to as 'SS51118')

      (Zhang et al., 2022, Wang et al., 2021, Wang et al., 2020)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Silencing neurons expressing Hsap\RELAAD.VT50405 and Scer\GAL4DBD.VT007068 renders virgin females sexually unreceptive to males. Elevated levels of egg laying are seen. Activating these neurons has no effect effect on virgin receptivity, but drastically increases receptivity after mating compared with controls.

      Silencing Ecol\lexAVT003280-expressing neurons does not suppress the increased receptivity to males seen in mated females when SAG-1 neurons (Hsap\RELAAD.VT50405 and Scer\GAL4DBD.VT007068-expressing) have been activated.

      (Feng et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Referred to as SAG-1 when in combination with Hsap\RELAAD.VT50405

      (Feng et al., 2014)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Scer\GAL4DBD.VT007068.T:Zzzz\Zip-
      Scer\GAL4DBD.VT007068
      Name Synonyms
      Secondary FlyBase IDs
        References (11)