FlyBase Allele Report: Dmel\ap[C2]

General Information

Symbol

Dmel\ap^C2

Species

D. melanogaster

Name

FlyBase ID

FBal0317143

Feature type

allele

Associated gene

Dmel\ap

Associated Insertion(s)

TI{TI}ap^C2

Carried in Construct

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

phiC31 integrase

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Bieli et al., 2015)

Mutagen

phiC31 integrase

(Bieli et al., 2015)

Progenitor genotype

TI{TI}ap^attPΔEnh

(Bieli et al., 2015)

Associated Insertion(s)

TI{TI}ap^C2

Cytology

Description

Block 2 of 5 conserved blocks of the ap enhancer region have been inserted into the attP site in TI{TI}ap^attPΔEnh, from which all 27kb of enhancer sequences have been removed.

(Bieli et al., 2015)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible (with ap^DG3)

(Bieli et al., 2015)

visible (with ap^DG12)

(Bieli et al., 2015)

Phenotype Manifest In

wing (with ap^DG3)

(Bieli et al., 2015)

wing (with ap^DG12)

(Bieli et al., 2015)

wing margin (with ap^DG3)

(Bieli et al., 2015)

Detailed Description

Statement

Reference

Wing defects are seen in ap^C2/ap^DG3 flies. Long wing stumps with defective wing margin and hinge are formed.

Defects are seen at the dorsoventral boundary of ap^C2/ap^DG12 mutant flies.

(Bieli et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

ap^C2

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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