FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Cbp53EUAS.cHa
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General Information
Symbol
Dmel\Cbp53EUAS.cHa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Hagel
FlyBase ID
FBal0318476
Feature type
allele
Associated gene
Dmel\Cbp53E
Associated Insertion(s)
Carried in Construct
P{UAS-Cbp53E.H}
Key Links
Transgenic product class
cDNA
(Hagel et al., 2015)
wild_type
(Hagel et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Hagel et al., 2015)
wild_type
(Hagel et al., 2015)
Mutagen
in vitro construct
(Hagel et al., 2015)
Progenitor genotype
Carried in construct
P{UAS-Cbp53E.H}
Cytology
Description

UAS regulatory sequences drive expression of a full-length Cbp53E cDNA including untranslated regions.

(Hagel et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Cbp53E
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of Cbp53EScer\UAS.cHa by Scer\GAL4elav.PU does not increase axon branching in type II/III/Ib terminals at the larval neuromuscular junction (NMJ). Overexpression of Cbp53EScer\UAS.cHa by Scer\GAL4how-24B reduces axon branching in type II/III (but not Ib) terminals at the larval NMJ.

      (Hagel et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Cbp53EUAS.cHa/Scer\GAL4elav.PU rescues Cbp53EMi22

      (Hagel et al., 2015)

      Cbp53EUAS.cHa/Scer\GAL4how-24B rescues Cbp53EMi22

      (Hagel et al., 2015)
      Comments

      Cbp53EScer\UAS.cHa driven by Scer\GAL4elav.PU or Scer\GAL4how-24B rescues increased axon branching at type II/III/Ib terminals seen in Cbp53EMi22/Cbp53EMi22 larval neuromuscular junctions.

      (Hagel et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Cbp53EScer\UAS.cHa
      Cbp53EUAS.cHa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Hagel
      Secondary FlyBase IDs
        References (1)