FlyBase Allele Report: Dmel\babo[DN.UAS.cUa]

General Information

Symbol

Dmel\babo^DN.UAS.cUa

Species

D. melanogaster

Name

FlyBase ID

FBal0319224

Feature type

allele

Associated gene

Dmel\babo

Associated Insertion(s)

Carried in Construct

P{UAS-babo.DN.U}

Key Links

Transgenic product class

dominant_negative_variant

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

dominant_negative_variant

(FlyBase Curators, 2025-)

Mutagen

in vitro construct

(FlyBase Curators, 2025-)

Progenitor genotype

Carried in construct

P{UAS-babo.DN.U}

Cytology

Description

UAS regulatory sequences drive expression of a dominant-negative form of babo.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

babo

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | adult stage | somatic clone, with Scer\GAL4^{DIP-γ-MI03222-GAL4}

(Luo et al., 2020)

Phenotype Manifest In

dendrite | adult stage | somatic clone, with Scer\GAL4^{DIP-γ-MI03222-GAL4}

(Luo et al., 2020)

distal medullary amacrine neuron Dm8a | adult stage | somatic clone, with Scer\GAL4^{DIP-γ-MI03222-GAL4}

(Luo et al., 2020)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^{DIP-γ-MI03222-GAL4}, babo^DN.UAS.cUa has abnormal neuroanatomy | somatic clone | adult stage phenotype, suppressible | partially by mTor^ΔP/mTor^ΔP

(Luo et al., 2020)

NOT Enhancer of

Statement

Reference

babo^DN.UAS.cUa/Scer\GAL4^{DIP-γ-MI03222-GAL4} is a non-enhancer of abnormal neuroanatomy | adult stage | somatic clone phenotype of Pten¹¹⁷

(Luo et al., 2020)

Suppressor of

Statement

Reference

babo^DN.UAS.cUa/Scer\GAL4^{DIP-γ-MI03222-GAL4} is a suppressor of abnormal neuroanatomy | somatic clone | adult stage phenotype of mTor^ΔP

(Luo et al., 2020)

NOT Suppressor of

Statement

Reference

babo^DN.UAS.cUa/Scer\GAL4^{DIP-γ-MI03222-GAL4} is a non-suppressor of abnormal neuroanatomy | somatic clone | adult stage phenotype of Pten¹¹⁷

(Luo et al., 2020)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^{DIP-γ-MI03222-GAL4}, babo^DN.UAS.cUa has distal medullary amacrine neuron Dm8a | somatic clone | adult stage phenotype, suppressible | partially by mTor^ΔP/mTor^ΔP

(Luo et al., 2020)

Scer\GAL4^{DIP-γ-MI03222-GAL4}, babo^DN.UAS.cUa has dendrite | somatic clone | adult stage phenotype, suppressible | partially by mTor^ΔP/mTor^ΔP

(Luo et al., 2020)

NOT Enhancer of

Statement

Reference

babo^DN.UAS.cUa/Scer\GAL4^{DIP-γ-MI03222-GAL4} is a non-enhancer of distal medullary amacrine neuron Dm8a | adult stage | somatic clone phenotype of Pten¹¹⁷

(Luo et al., 2020)

babo^DN.UAS.cUa/Scer\GAL4^{DIP-γ-MI03222-GAL4} is a non-enhancer of dendrite | adult stage | somatic clone phenotype of Pten¹¹⁷

(Luo et al., 2020)

Suppressor of

Statement

Reference

babo^DN.UAS.cUa/Scer\GAL4^{DIP-γ-MI03222-GAL4} is a suppressor of distal medullary amacrine neuron Dm8a | somatic clone | adult stage phenotype of mTor^ΔP

(Luo et al., 2020)

babo^DN.UAS.cUa/Scer\GAL4^{DIP-γ-MI03222-GAL4} is a suppressor of dendrite | somatic clone | adult stage phenotype of mTor^ΔP

(Luo et al., 2020)

NOT Suppressor of

Statement

Reference

babo^DN.UAS.cUa/Scer\GAL4^{DIP-γ-MI03222-GAL4} is a non-suppressor of distal medullary amacrine neuron Dm8a | somatic clone | adult stage phenotype of Pten¹¹⁷

(Luo et al., 2020)

babo^DN.UAS.cUa/Scer\GAL4^{DIP-γ-MI03222-GAL4} is a non-suppressor of dendrite | somatic clone | adult stage phenotype of Pten¹¹⁷

(Luo et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

babo^{DN.Scer\UAS.cUa}

babo^DN.UAS.cUa

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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