FB2026_02 , released June 18, 2026
Allele: Dmel\CycGeoC
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General Information
Symbol
Dmel\CycGeoC
Species
D. melanogaster
Name
FlyBase ID
FBal0319257
Feature type
allele
Associated gene
Dmel\CycG
Associated Insertion(s)
TI{TI}CycGeoC
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Fischer et al., 2015)
Mutagen
ends-out gene targeting
(Fischer et al., 2015)
Progenitor genotype
Associated Insertion(s)
TI{TI}CycGeoC
Cytology
Description

Deletion of almost all the CycG coding region. A single loxP site is present at the site of the deletion.

(Fischer et al., 2015)
Allele components
Component
Use(s)
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      CycGeoC homozygote females are sterile and display egg patterning defects.

      CycGeoC females lay significantly fewer eggs per day than controls.

      CycGeoC homozygous mutants are developmentally delayed, smaller and lighter than wild-type controls.

      CycGeoC homozygous larvae contain more fat than controls.

      CycGeoC/CycGHR7 transheterozygotes show developmental delay, reduced body size and weight, higher fat content and decreased egg laying rate.

      (Fischer et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      CycGeoC, Df(1)N-54l9/+ has visible phenotype

      (Nagel et al., 2016)
      Phenotype Manifest In
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      CycGeoC/CycGeoC;Df(1)N-54l9/+ adult flies display less penetrant wing notching than CycGeoC/+;Df(1)N-54l9/+ double heterozygotes but more than Df(1)N-54l9/+ single heterozygotes.

      (Nagel et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      CycGHR7

      (Fischer et al., 2015)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CycGeoC
      cycGeoC
      (Nagel et al., 2016, Fischer et al., 2015)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)